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The upcoming MLB game between the St. Louis Cardinals and Pittsburgh Pirates is scheduled for April 28, 2026, at PNC Park in Pittsburgh, PA, broadcast on SNP. Our picks predict a Pittsburgh win with a projected score of 5.16 to 3.60, favoring Pittsburgh at -1.5 spread. Pittsburgh's hitters perform well against right-handed pitchers, which is crucial as the probable starter is right-handed. Our model shows a profitable betting record with a 65.4% hit rate on Pittsburgh 2-way bets and positive EV, supporting confident betting tips for this matchup. Explore more detailed MLB picks and predictions on our MLB picks page.
![]() CWSA. Kay (L) 30-27100% +118Everygame | |||||||
WSHF. Griffin (L) 29-29- +111Bet105 | |||||||
BALB. Young (R) 26-32- +110Bet105 | |||||||
![]() TEXK. Rocker (R) 26-31- -117Bookmaker | |||||||
PITM. Keller (R) 30-28- -132Bet105 | |||||||
NYMC. Scott (R) 24-330% -127Bookmaker | |||||||
TBD. Rasmussen (R) 35-190% -147Bet105 | |||||||
![]() CLEP. Messick (L) 34-25- -125BetOnline | |||||||
HOUP. Lambert (R) 26-33- +100BetOnline | |||||||
STLK. Leahy (R) 30-25100% +130Everygame | |||||||
CINB. Singer (R) 29-27100% +126BetOnline | |||||||
![]() COLR. Feltner (R) 21-37- +116Everygame | |||||||
![]() ATHJ. Ginn (R) 27-300% +135Everygame | |||||||
LADR. Sasaki (R) 37-20- -125BetOnline | |||||||
SEAB. Woo (R) 29-29- -149Bet105 |