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The MLB matchup between Pittsburgh Pirates and St. Louis Cardinals is scheduled for May 19, 2026, at Busch Stadium in St. Louis, MO. Broadcast on card, the game features predicted scores of 4.40 for Pittsburgh and 4.34 for St. Louis, with an expected total of 8.74 runs. Our picks favor St. Louis covering the +1.5 spread with a 64.6% probability and a positive EV of 0.3%. Pittsburgh's hitters have a slightly better performance against right-handed pitching, which may influence betting tips. Our prediction model has been profitable in recent games, particularly excelling in point spread markets with a high hit rate. For more detailed MLB picks and predictions, visit MLB Picks and Predictions.
![]() DETT. Melton (R) 31-44- -135BetOnline | |||||||
NYYW. Warren (R) 46-28- -185BetOnline | |||||||
![]() CHCC. Rea (R) 40-36- -120BetOnline | |||||||
![]() TEXN. Eovaldi (R) 36-39- -126Bet105 | |||||||
ATLC. Sale (L) 47-2767% -125BetOnline | |||||||
MIAM. Meyer (R) 38-380% -130Bet105 | |||||||
TBI. Seymour (L) 42-30100% -115Everygame | |||||||
PHIC. Sánchez (L) 40-3575% -173Bet105 | |||||||
HOUS. Arrighetti (R) 36-410% -130Bookmaker | |||||||
![]() COLT. Sugano (R) 29-47- +178Bookmaker | |||||||
![]() ATHJ. Ginn (R) 38-38- -160BetOnline | |||||||
SEAE. Hancock (R) 39-38- -120BetOnline | |||||||
LADY. Yamamoto (R) 49-27100% -239Bet105 | |||||||
![]() AZZ. Gallen (R) 39-360% -127BetOnline |