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The MLB showdown between the St. Louis Cardinals and the San Francisco Giants is set for September 5, 2025, at Busch Stadium in St. Louis, MO. As the Cardinals host the Giants, fans and bettors alike are buzzing with anticipation. This game promises to be a thrilling contest, and with the Cardinals listed as favorites with -1½ -110 on the run line, there's a lot at stake. The Giants, currently underdogs, have a run line of +1½ -110.
For those looking to place a bet, the odds are intriguing. The Cardinals' moneyline odds are -120 at Caesars, while the Giants are at +100. With the over/under set at 8½, this game is expected to be a tight contest. Ensure you're ready to make informed bets by visiting our MLB odds page for the latest updates.
Catch all the action live on FDSMW and don't miss out on the excitement. Whether you're a seasoned bettor or new to the game, understanding the odds and betting lines is crucial. The opening odds had the Cardinals slightly favored, but as the game approaches, shifts in the line reflect changing dynamics. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1230% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1116% -106BetAnything | |||||||
TBS. Matz (L) 12-1076% +103BetOnline | |||||||
WSHF. Griffin (L) 10-1373% +127Bet105 | |||||||
BOSC. Early (L) 9-1351% -121Everygame | |||||||
NYMN. McLean (R) 7-1525% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-916% -125Bookmaker | |||||||
KCK. Bubic (L) 7-1612% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1478% +133Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1380% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1426% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-913% -142Bet105 | |||||||
SFL. Roupp (R) 9-1390% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |