- Run Line
- Money
- Total
- Merged
The San Francisco Giants and St. Louis Cardinals are set to square off on September 6, 2025, at Busch Stadium in St. Louis, MO. As part of the MLB league, this game will be broadcasted on Fox, giving fans a chance to catch the action live. With the Giants currently favored, the betting odds reflect a -130 moneyline for San Francisco, while the Cardinals hold a +110 line. The run line sees the Giants at -1.5 +130 and the Cardinals at +1.5 -155. The total over/under is set at 8.5, with the under being slightly favored at -115. These odds have shifted from their opening lines, indicating a growing confidence in the Giants' performance. Bettors should consider the Giants' recent form and the Cardinals' home advantage when placing wagers. This matchup's insights can guide bettors to make informed decisions, particularly when considering the run line and total markets. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more insights, check the MLB odds page.
MIAJ. Junk (R) 11-1341% -135BetOnline | |||||||
![]() CLET. Bibee (R) 14-1118% -147Bookmaker | |||||||
TBN. Martinez (R) 12-1159% -133Bet105 | |||||||
KCM. Wacha (R) 8-166% -130Everygame | |||||||
LAAJ. Soriano (R) 11-1423% -142BetAnything | |||||||
SEAL. Gilbert (R) 10-1536% -175BetOnline | |||||||
![]() DETC. Mize (R) 12-1285% -129BetOnline | |||||||
WSHZ. Littell (R) 11-1396% +133Bookmaker | |||||||
BOSR. Suarez (L) 9-1477% +126Everygame | |||||||
NYMC. Holmes (R) 7-160% -140Heritage | |||||||
![]() CHCM. Boyd (L) 14-919% -162Bet105 | |||||||
![]() TEXJ. Leiter (R) 12-1157% +102Bookmaker | |||||||
![]() COLT. Sugano (R) 9-1589% +140Everygame | |||||||
![]() AZE. Rodriguez (L) 13-106% -136Heritage | |||||||
SFT. Mahle (R) 10-1392% +186Bookmaker |