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The upcoming MLB game on April 25, 2026, features the Seattle Mariners visiting the St. Louis Cardinals at Busch Stadium in St. Louis, MO. Broadcasted on SEAM, the match presents an analytical edge favoring Seattle based on our picks and predictions. Our model projects a final score of Seattle 4.3 to St. Louis 3.0, with Seattle slightly less favored to cover the -1.5 spread at 46.5% probability, while St. Louis holds a 53.5% chance to cover the +1.5 spread. The total score is expected to stay under 8, supported by a 61.7% hit rate and a positive EV of 6.1%. Seattle's hitters have demonstrated competent performance against right-handed pitchers, aligning with the starting pitcher profile, which influences our betting tips. Our prediction model has maintained profitability in similar markets over the last 10 games, winning 6 out of 10 in American totals. For more detailed analysis, explore our MLB picks and predictions.
TBC. Legumina (R) 44-3343% -132Bet105 | |||||||
PITB. Chandler (R) 40-4073% +135Everygame | |||||||
SFL. Roupp (R) 33-4655% -122Bookmaker | |||||||
![]() DETT. Melton (R) 34-4670% -108BetAnything | |||||||
WSHC. Cavalli (R) 41-4071% +170Bookmaker | |||||||
![]() TORK. Gausman (R) 39-4121% -144Bet105 | |||||||
NYMF. Peralta (R) 34-4616% -105Bet105 | |||||||
BOSC. Early (L) 32-4672% +145Everygame | |||||||
STLM. McGreevy (R) 42-3613% -129BetOnline |