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The St. Louis Cardinals face the Washington Nationals at Nationals Park in Washington, DC, on April 8, 2026, broadcast on nats. The betting odds show Cardinals as favorites with a run line of -1.5 +130, while Nationals are at +1.5 -150. Opening run lines have shifted to reflect increased confidence in the Cardinals. Totals are set at 8.5 with the under favored at -120. This data-driven odds analysis provides valuable insights ahead of this MLB regular season game. For more details, visit the MLB odds page.
TBC. Legumina (R) 44-3342% -135BetAnything | |||||||
PITB. Chandler (R) 40-4071% +135Everygame | |||||||
SFL. Roupp (R) 33-4657% -122Bookmaker | |||||||
![]() DETT. Melton (R) 34-4667% -104Bookmaker | |||||||
WSHC. Cavalli (R) 41-4070% +155Heritage | |||||||
![]() TORK. Gausman (R) 39-4118% -144Bet105 | |||||||
NYMF. Peralta (R) 34-4618% -102Bookmaker | |||||||
BOSC. Early (L) 32-4668% +145Everygame | |||||||
STLM. McGreevy (R) 42-3612% -129BetOnline |