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On October 18, 2025, Saturday football brings the USC Trojans vs Notre Dame Fighting Irish to Notre Dame Stadium in South Bend, IN. NBC will broadcast this Week 8 NCAAF showdown, and oddsmakers have released the latest odds for bettors to consider.
The point spread opened with the Fighting Irish at -7 -110 but has surged to -9 -110, reflecting significant backing for Notre Dame. This two-point adjustment highlights how real-time money flow and expert action can reshape betting markets.
Check out updated NCAAF odds. The best lines available feature +9 -110 for USC Trojans at Caesars and -9 -110 for Notre Dame Fighting Irish at Caesars.
By comparing these betting lines to each team’s statistical profiles—Notre Dame’s top-five scoring defense (allowing just 16.4 points per game) versus USC’s inconsistent road offense (averaging 22.3 points away)—bettors can pinpoint value and make smarter decisions.
The Irish’s 12-1 record at home underscores the impact of Notre Dame Stadium’s crowd, while the Trojans have dropped three of their last four road games. Understanding these trends gives you a strategic edge.
Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your wager with a U.S. regulated sportsbook and profit off the edge.
![]() Jacksonville State 3-368% +3 -110Caesars | |||||||
![]() Sam Houston State 0-664% +3 -121BetRivers | |||||||
East Carolina 3-365% -17 -109BetRivers | |||||||
![]() #2Miami (FL) 5-042% -13½ -110Caesars | |||||||
Minnesota 4-240% +8½ -112FanDuel | |||||||
![]() Utah State 3-330% -3½ -104FanDuel | |||||||
![]() California 4-241% -9½ -118BetRivers | |||||||
Miami (OH) 3-30% -12½ -115FanDuel | |||||||
![]() Boston College 1-577% -1½ -110Bet365 | |||||||
![]() Duke 4-282% -1½ -110Caesars | |||||||
Bowling Green 3-331% -3½ -120FanDuel | |||||||
![]() #17Vanderbilt 5-157% -2½ -110Caesars | |||||||
![]() Michigan 4-253% -5½ -115BetMGM | |||||||
![]() Houston 5-150% +1½ -115BetMGM | |||||||
TCU 4-247% -2½ -121SugarHouse | |||||||
![]() Tulane 5-122% -9½ -110Bet365 | |||||||
![]() South Carolina 3-375% +6 -117SugarHouse | |||||||
UCF 3-325% -7 -112BetRivers | |||||||
![]() Toledo 3-343% -26½ -110Caesars | |||||||
![]() Massachusetts 0-6100% +17 -110Caesars | |||||||
![]() Louisiana-Monroe 3-3100% +6½ -110BetRivers | |||||||
![]() Northwestern 4-230% -3 -113Caesars | |||||||
Appalachian State 4-20% -10½ -105FanDuel | |||||||
![]() Ohio 3-30% -11 -110Caesars | |||||||
![]() James Madison 5-127% -1½ -105BetMGM | |||||||
![]() Charlotte 1-5100% +11½ -110Caesars | |||||||
![]() Clemson 3-331% -8½ -113SugarHouse | |||||||
![]() #3Indiana 6-024% -27 -112BetRivers | |||||||
Marshall 3-367% +3 -114BetRivers | |||||||
Ball State 2-40% -1½ +100BetMGM | |||||||
![]() Boise State 4-257% -11½ -110BetMGM | |||||||
![]() North Texas 5-130% -4 -110Caesars | |||||||
![]() #9Georgia 5-153% -7 -115BetMGM | |||||||
![]() Arkansas 2-480% +8 -115SugarHouse | |||||||
![]() Wisconsin 2-495% +26½ -110FanDuel | |||||||
Air Force 1-529% -3½ -115FanDuel | |||||||
UAB 2-425% +21½ -110Caesars | |||||||
![]() Arizona State 4-240% +9½ -110Caesars | |||||||
Florida 2-436% -8½ -113BetRivers | |||||||
![]() Louisiana 2-467% +4 -113BetRivers | |||||||
![]() #18Virginia 5-10% -17 -105Caesars | |||||||
Rutgers 3-3100% +17½ -115FanDuel | |||||||
![]() Georgia Southern 2-411% -6½ -110Bet365 | |||||||
![]() Colorado State 2-460% -2½ -110Bet365 | |||||||
UCLA 2-433% -3 -120SugarHouse | |||||||
Iowa 4-278% -2½ -118FanDuel | |||||||
Kentucky 2-369% +12½ -110Caesars | |||||||
![]() #19South Florida 5-10% -21½ -110Caesars | |||||||
Syracuse 3-329% +11 -112BetRivers | |||||||
#13Notre Dame 4-261% -9 -110Caesars | |||||||
#6Alabama 5-130% -7½ -118FanDuel | |||||||
Auburn 3-362% +2 -114BetRivers | |||||||
Oklahoma State 1-587% +22 -109SugarHouse | |||||||
#15Brigham Young 6-058% +3½ -110BetMGM | |||||||
![]() New Mexico 3-30% -11½ -110Caesars | |||||||
![]() Oregon State 0-7- -20½ -110FanDuel | |||||||
Stanford 2-475% +18 -110Caesars | |||||||
![]() Liberty 3-430 -10½ -108Caesars | |||||||
![]() South Alabama 1-614 -7½ -115BetMGM | |||||||
![]() Western Kentucky 5-26 -10 -110Bet365 |
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