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The upcoming showdown on November 29, 2025, between the South Carolina Gamecocks and Clemson Tigers at Williams-Brice Stadium in Columbia, SC, is a must-watch in the 2025-26 NCAAF season. This Saturday football game is broadcasted on SEC Network and ESPN Networks, providing ample coverage for fans and bettors alike.
South Carolina enters as the favorite with a point spread of -2.5, indicating a slight edge over Clemson. The total points line is set at 46.5, suggesting a moderately scoring affair. South Carolina's offense, led by their starting quarterback, faces a Clemson defense that ranks well in limiting passing yards, allowing just around 211.6 yards per game. Clemson's offense, meanwhile, averages 274.5 passing yards and 129.8 rushing yards, posing a balanced threat against South Carolina's defense which allows about 328.5 total yards per game.
Betting trends show that South Carolina holds a 6-5 record against the spread this season, particularly strong at home with a 4-3 ATS record. Clemson, on the other hand, has struggled against the spread with a 4-7 record, though they perform better on the road with a 3-1 ATS record. This matchup's betting insights reveal that South Carolina's advantage in run defense against Clemson's run offense could be a significant factor in controlling the game's pace.
Quarterback play will be crucial, with South Carolina's starter expected to perform well despite a questionable tag, likely taking the field. Clemson's balanced attack and slightly better pass protection versus South Carolina's pass rush will be a key battle area. The previous close encounter on November 30, 2024, ended with South Carolina narrowly winning 17-14, showing how tightly contested these games can be.
For bettors, understanding these betting trends and game stats can offer an edge. The odds spread and total points line provide a framework for strategic wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Don't miss this high-stakes NCAAF game between the South Carolina Gamecocks and Clemson Tigers, live from Williams-Brice Stadium on November 29, 2025.
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Eastern Michigan 4-775% +7½ -109Caesars | |||||||
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Buffalo 5-675% +7 -110Bet365 | |||||||
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Nebraska 7-479% +6½ -112BetRivers | |||||||
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West Virginia 4-775% +24 -115SugarHouse | |||||||
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Louisville 7-425% -3 -110Bet365 | |||||||
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Central Michigan 7-467% +10½ -110BetMGM | |||||||
Miami (OH) 6-5- -17½ -110Bet365 | |||||||
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Baylor 5-643% -2½ -105Bet365 | |||||||
Oklahoma State 1-10100% +14½ -115FanDuel | |||||||
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![]() Sam Houston State 2-9100% +11 -115SugarHouse | |||||||
#11Brigham Young 10-10% -17½ -110BetMGM | |||||||
Marshall 5-60% -7 -110Bet365 | |||||||
![]() Old Dominion 8-350% -26½ -110BetMGM | |||||||
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Appalachian State 5-6100% -2½ -109Caesars | |||||||
Syracuse 3-8100% +3½ -122FanDuel | |||||||
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Texas State 5-60% -9½ -106Caesars | |||||||
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Rutgers 5-6100% +13½ -114FanDuel | |||||||
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TCU 6-457% -3½ -110Caesars | |||||||
Southern Miss 7-467% -6 -120SugarHouse | |||||||
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Minnesota 6-517% -1 -105Bet365 | |||||||
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Florida 3-80% +1½ -115BetMGM | |||||||
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Michigan State 3-850% -3½ -110BetRivers | |||||||
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![]() North Carolina State 6-525% -7½ -105FanDuel | |||||||
Auburn 5-6100% +6 -115SugarHouse | |||||||
#24Tulane 9-20% -29½ -110BetMGM | |||||||
#21Illinois 7-412% -6½ -115Bet365 | |||||||
#15USC 8-260% -21½ -110FanDuel | |||||||
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Stanford 4-7100% +32½ -108Caesars | |||||||
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