Dec 6, 2025 8:00 PM ESTACC Championship

Week 15

Duke

10-2

#17 Virginia

UVA

-3½ (-105)o57½ (-115)

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Duke Blue Devils vs Virginia Cavaliers Odds

Updated:Dec 4, 2025 1:36 AM EST

The upcoming Saturday football showdown on December 6, 2025, features the Duke Blue Devils visiting the Virginia Cavaliers at Bank of America Stadium in Charlotte, NC. This thrilling NCAAF regular season Week 15 game promises intense action and strategic gameplay, perfect for bettors looking to capitalize on the latest odds and betting lines.

The current odds favor the Virginia Cavaliers as favorites at -3½ -108, with opening odds slightly different, indicating some market movement that savvy bettors should note. Duke Blue Devils are the underdogs with a +3½ -112 point spread, offering a compelling betting opportunity. The over/under total is set at 57½, with the over at -114 and under at -106.

Broadcast on ABC, this game provides a prime opportunity to watch and wager simultaneously. The venue, Bank of America Stadium in Charlotte, NC, sets the stage for an exciting clash between these two competitive teams. Understanding these odds and betting odds can help bettors make smarter decisions and find value bets.

For those eager to dive deeper, the NCAAF odds page offers comprehensive insights and up-to-date lines. Ready to bet smarter? Start your OddsTrader Turbo subscription today or place your bet with a U.S. regulated sportsbook and gain the edge with expert analysis.

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NCAAF

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NCAAF Fri 12/05

Personalize your notifications and get updates on the teams, players or events you care about most. FRI 12/057:00 PMConference USA Championship Kennesaw State 9-3 51% -2½ -109Caesars
Jacksonville State 8-4 49% +2½ -108BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 12/057:00 PMSun Belt Championship Troy 8-4 68% +23½ -105Caesars
#25James Madison 11-1 32% -23 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 12/058:00 PMAmerican Athletic Conference Championship #24North Texas 11-1 42% -2½ -110Bet365
#20Tulane 10-2 58% +3 -125SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 12/058:00 PMMountain West Championship UNLV 10-2 67% +4½ -108Caesars
Boise State 8-4 33% -3½ -120BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 12/0612:00 PMBig 12 Championship #11Brigham Young 11-1 69% +12½ -102Caesars
#4Texas Tech 11-1 31% -12½ -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 12/0612:00 PMMAC Championship Miami (OH) 7-5 55% +2½ -110Bet365
Western Michigan 8-4 45% -1½ -114FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 12/064:00 PMSEC Championship #3Georgia 11-1 63% -2½ -113Caesars
#9Alabama 10-2 37% +3 -121BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 12/068:00 PMACC Championship Duke 7-5 77% +3½ -110Bet365
#17Virginia 10-2 23% -3½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 12/068:00 PMBig Ten Championship #2Indiana 12-0 51% +4½ -105BetMGM
#1Ohio State 12-0 49% -4 -110Bet365

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