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The upcoming Saturday football game on November 22, 2025, features the Mississippi Valley State Delta Devils visiting the Prairie View A&M Panthers at Panther Stadium at Blackshear Field in Prairie View, TX. This NCAAF regular season Week 13 matchup promises intriguing betting trends for sports bettors. Prairie View A&M Panthers boast a strong 8-3 straight-up record and a 7-3 against-the-spread record, making them a formidable home team. Mississippi Valley State Delta Devils, on the other hand, struggle with a 1-9 straight-up record and 4-5 ATS, showing a clear underdog status.
Game insights reveal that Prairie View A&M has a more potent offense, averaging 424 total yards per game with a strong passing game led by their starting quarterback, who is healthy and expected to play. Their defense is solid against passing but vulnerable against the run. Mississippi Valley State's defensive stats show decent pass defense but weaker run defense, which Prairie View could exploit with their run game averaging 199.9 yards per game. The Delta Devils’ offense struggles, averaging just 297.7 total yards, with a weaker passing game facing a tough pass rush from Prairie View’s defense.
The odds spread is currently not listed, but given Prairie View's home advantage, better records, and offensive stats, they are likely favorites. The total points line is also not listed, but past matchups have generally gone under the total points line. This matchup is broadcast on SWAC Digital Net and SWAC TV, making it accessible for fans and bettors alike.
Reviewing their last close game on November 2, 2024, where Prairie View edged Mississippi Valley State 17-16, bettors can expect a competitive game. Prairie View’s strong ATS record and home field advantage provide solid betting trends to consider. The Panthers’ ability to protect their quarterback against the Delta Devils’ pass rush will be key, as will Mississippi Valley State’s efforts to contain Prairie View’s rushing attack. The Panthers’ balanced attack and superior defense make them the best bet for this game.
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