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The upcoming Saturday football clash on November 22, 2025, between the Mississippi Valley State Delta Devils and Prairie View A&M Panthers at Panther Stadium at Blackshear Field in Prairie View, TX, is set to be an intriguing NCAAF matchup. Both teams bring contrasting strengths to the gridiron that could heavily influence betting trends for this game.
Mississippi Valley State has struggled this season with a 1-9 straight-up record and a 4-5 mark against the spread, showing vulnerabilities particularly in their passing defense, allowing an average of 228.7 passing yards per game. Their starting quarterback, despite some injury concerns, is expected to play and will need to overcome Prairie View A&M's solid pass rush, which averages 1.45 sacks per game. Offensively, Mississippi Valley State averages 190.8 passing yards and 106.9 rushing yards per game, but their overall yardage per play is lower than Prairie View A&M’s 6.73 yards.
The Prairie View A&M Panthers, with an 8-3 record and 7-3 ATS, have been strong at home with a 4-2 record. Their defense limits opponents to just 129.7 passing yards per game, and their offense boasts a balanced attack with 224.1 passing yards and 199.9 rushing yards per game. Their starting quarterback is healthy and leads a well-coordinated offense that can exploit Mississippi Valley State's weaker pass protection and run defense.
Recent betting trends favor Prairie View A&M with a home advantage and a spread that typically leans in their favor. The total points line has often gone under in their matchups, consistent with both teams’ defensive capabilities. The best bet would be to back Prairie View A&M to cover the spread while considering the under for total points.
The game will be broadcast on SWAC Digital Net and SWAC TV, providing ample viewing options. For bettors seeking game insights and to maximize their betting edge, the detailed stats and trends point to Prairie View A&M Panthers as the smart pick this Saturday. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on November 2, 2024, the Prairie View A&M Panthers edged out Mississippi Valley State by a narrow 17-16 score, highlighting the competitive nature of this rivalry.
The Panthers have a strong home record, which you can see on our NCAAF standings page.
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