As the Buffalo Bulls gear up to take on the Minnesota Golden Gophers on August 28, 2025, at Huntington Bank Stadium in Minneapolis, MN, the excitement is palpable. The Thursday night football clash marks the start of the 2025-26 NCAAF season, and both teams are eager to make a strong impression. Minnesota, playing at home, will look to leverage their defensive prowess, while Buffalo aims to counter with their offensive strategies.

In their last matchup on August 31, 2017, Minnesota emerged victorious with a 17-7 win over Buffalo. This time, the Gophers are favored again with a point spread of -17.5, reflecting their strength in recent games. Buffalo, however, has shown resilience, winning four of their last five games, including a notable 37-20 victory against Eastern Michigan.

Quarterback play will be crucial, with Minnesota's starting QB expected to lead a robust passing offense against Buffalo's defense. The Gophers' pass protection and rush defense are set to challenge Buffalo's run offense. Meanwhile, Buffalo's QB will need to navigate Minnesota's pass rush effectively.

For bettors, the odds spread offers intriguing opportunities. The over/under is set at 43.5 points, suggesting a potentially tight game. Considering the teams' recent performances, betting insights suggest keeping an eye on how both teams perform in the red zone and handle turnovers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.