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The upcoming Saturday football clash on November 29, 2025, between the South Carolina Gamecocks and Clemson Tigers at Williams-Brice Stadium in Columbia, SC, promises an exciting showdown in the 2025-26 NCAAF season. The Gamecocks, favored by a 2.5-point spread with odds of -118 at Caesars, will rely on their strong pass protection and run defense to contain Clemson's dynamic offense. Clemson, with a +2.5 spread at -102 odds, aims to leverage its potent pass offense and a solid pass rush to disrupt South Carolina's game plan.
South Carolina's starting quarterback is expected to lead the offense, supported by a robust rushing attack averaging 35.6 yards per game. Clemson counters with a balanced offensive strategy, averaging over 404 yards per game, including a notable passing yardage of 274.5. Defensively, South Carolina holds a slight edge in interceptions and sacks, which could be pivotal in this tightly contested game.
Recent form shows Clemson with a mix of wins and losses but a strong scoring ability, including a dominant 45-10 win over Boston College. South Carolina, meanwhile, has showcased resilience with key victories and tight losses, maintaining a competitive edge at home. The total points line is set at 47 with an under favorite at -110, reflecting expectations of a moderately paced game with solid defensive plays.
Betting trends indicate a close matchup with South Carolina's home advantage and Clemson's offensive firepower balancing the scales. Game insights suggest watching the quarterback duel and the effectiveness of the run game on both sides to make smart betting decisions. This game will be broadcast on SEC Network and ESPN Networks, providing ample coverage for fans and bettors alike.
For bettors looking to capitalize on these betting trends, the best odds today for South Carolina are -2.5 at Caesars, while Clemson sits at +2.5 at Caesars. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on November 30, 2024, where South Carolina edged Clemson 17-14, the Gamecocks narrowly defeated the Tigers, highlighting the intense rivalry and competitive nature of this matchup.
West Virginia 4-773% +24½ -130BetMGM | |||||||
![]() Florida Atlantic 4-782% +7 -105BetMGM | |||||||
Louisville 7-415% -2½ -110Bet365 | |||||||
![]() South Carolina 3-732% -2½ -110Bet365 | |||||||
![]() #15Michigan 9-273% +10½ -122FanDuel | |||||||
![]() #22Pittsburgh 8-363% +7 -110Caesars | |||||||
Central Michigan 7-454% +11½ -115FanDuel | |||||||
Miami (OH) 6-550% -17½ -105Bet365 | |||||||
![]() Kansas State 5-635% -17 -110Bet365 | |||||||
Baylor 5-643% -2½ -114Caesars | |||||||
Oklahoma State 1-1081% +14 -110BetMGM | |||||||
![]() Delaware 5-630% -3½ -118FanDuel | |||||||
![]() Sam Houston State 2-971% +11½ -113BetRivers | |||||||
#11Brigham Young 10-166% -17½ -106FanDuel | |||||||
Marshall 5-622% -10 -110Bet365 | |||||||
![]() Old Dominion 8-327% -27½ -110Bet365 | |||||||
![]() Missouri State 7-429% -2½ -110Bet365 | |||||||
![]() Jacksonville State 7-427% +3 -115BetMGM | |||||||
Appalachian State 5-643% -1½ -102FanDuel | |||||||
Syracuse 3-840% +3 -108BetRivers | |||||||
![]() Tulsa 4-745% -8½ -110Bet365 | |||||||
Texas State 5-640% -8½ -115FanDuel | |||||||
![]() Louisiana 5-620% -8½ -114SugarHouse | |||||||
New Mexico State 4-767% -3½ -105BetMGM | |||||||
#19Tennessee 8-336% -2½ -112FanDuel | |||||||
![]() Duke 6-546% -1 -110Bet365 | |||||||
Rutgers 5-694% +14 -118BetRivers | |||||||
![]() #8Oklahoma 9-264% -10½ -110Bet365 | |||||||
![]() UTSA 6-537% -7 -120SugarHouse | |||||||
TCU 6-487% -3 -124BetRivers | |||||||
Southern Miss 7-450% -6 -118SugarHouse | |||||||
![]() Arkansas 2-980% +4 -112Caesars | |||||||
Minnesota 6-534% +2½ -115Caesars | |||||||
![]() Washington 8-373% +7 -110Bet365 | |||||||
![]() Liberty 4-779% +2½ -115SugarHouse | |||||||
![]() Coastal Carolina 6-587% +22 -109Caesars | |||||||
Florida 3-827% -½ -115SugarHouse | |||||||
![]() Washington State 5-647% -13 -115BetRivers | |||||||
![]() South Florida 8-35% -28 -107Caesars | |||||||
Michigan State 3-895% -3½ -114FanDuel | |||||||
![]() #18Virginia 9-219% -8 +100Bet365 | |||||||
![]() North Carolina State 6-524% -7 -110Caesars | |||||||
Auburn 5-682% +6 -113BetRivers | |||||||
#24Tulane 9-28% -29½ -115BetMGM | |||||||
Illinois 7-413% -7 -110Bet365 | |||||||
#17USC 8-242% -21½ -108FanDuel | |||||||
![]() California 6-548% +13½ -110Bet365 | |||||||
![]() Nevada 3-874% +7½ -110Bet365 | |||||||
![]() San Jose State 3-886% +3½ -109Caesars | |||||||
Stanford 4-778% +32½ -110BetMGM | |||||||
![]() Hawaii 7-417% -7½ -110Caesars | |||||||
![]() Massachusetts 0-1214 +14½ -110Bet365 | |||||||
Eastern Michigan 4-821 +10 -105BetMGM | |||||||
![]() Memphis 8-417 -3½ -112Caesars | |||||||
Buffalo 5-726 +7½ -120FanDuel | |||||||
![]() Mississippi State 5-719 +8 -127SugarHouse | |||||||
Nebraska 7-516 +6 +100Caesars | |||||||
![]() Northern Illinois 3-931 -4½ -115Bet365 | |||||||
![]() Kansas 5-721 +10½ -115Caesars | |||||||
![]() Colorado State 2-1021 +2½ -105FanDuel | |||||||
![]() #23Georgia Tech 9-39 +16½ -105BetMGM | |||||||
![]() New Mexico 9-323 +1½ -115BetMGM | |||||||
![]() North Texas 11-152 -20 -112SugarHouse | |||||||
![]() Utah State 6-624 +1½ -105FanDuel | |||||||
![]() #16Texas 9-327 +2½ +100Caesars | |||||||
![]() Purdue 2-103 +29 -113BetRivers | |||||||
![]() #20Arizona State 8-47 +2 -107Caesars |
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