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The upcoming clash on November 29, 2025, between the South Carolina Gamecocks and Clemson Tigers at Williams-Brice Stadium in Columbia, SC, is set to be a thrilling display of college football in the NCAAF league. This Saturday football matchup features South Carolina as the home favorite with a point spread of -2.5 and total points set at 46.5, making it a strategic game for bettors focusing on the betting trends.
South Carolina's defense has been robust, allowing just 211.6 passing yards per game and ranking well in sacks, while Clemson's offense averages 274.5 passing yards with a strong passing attack led by their starting quarterback. Clemson's defense is solid too, but South Carolina's run defense and pass rush might challenge Clemson's offensive line and quarterback protection.
Both teams have shown varied success against the spread this season, with South Carolina holding a 6-5 ATS record and Clemson sitting at 4-7. Recent performances highlight Clemson's high-scoring capability, including a 45-point win over Furman, while South Carolina has demonstrated resilience with a strong home record. Bettors should consider these game insights when making their wagers.
The game will be broadcast on SEC Network and ESPN Networks, providing fans and bettors ample opportunity to catch all the action live. For those looking to gain an edge, the best odds today have South Carolina favored at -141 and Clemson at +117 on Caesars sportsbook. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
For context, their last matchup on November 30, 2024, was a nail-biter with South Carolina winning 17-14 at Memorial Stadium, Clemson. This close contest adds extra excitement to the upcoming game as both teams vie for supremacy in this storied rivalry.
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Buffalo 5-672% +7 -110Bet365 | |||||||
![]() Mississippi State 5-681% +7½ -120FanDuel | |||||||
Nebraska 7-475% +6 -110BetMGM | |||||||
![]() Northern Illinois 3-818% -5 -110Bet365 | |||||||
![]() Kansas 5-673% +11½ -110Bet365 | |||||||
![]() Colorado State 2-967% +2½ -108BetRivers | |||||||
![]() #23Georgia Tech 9-226% +14 -110BetMGM | |||||||
![]() New Mexico 8-388% +1½ -114Caesars | |||||||
![]() North Texas 10-149% -19½ -110Bet365 | |||||||
![]() Utah State 6-582% +3 -105BetMGM | |||||||
![]() #16Texas 8-389% +2½ -110BetMGM | |||||||
![]() Purdue 2-982% +29½ -120BetMGM | |||||||
![]() #20Arizona State 8-337% +2 -112BetRivers | |||||||
West Virginia 4-787% +23½ +100Bet365 | |||||||
![]() Florida Atlantic 4-778% +7 -105BetMGM | |||||||
Louisville 7-41% -2½ -118FanDuel | |||||||
![]() South Carolina 3-725% -2½ -110Bet365 | |||||||
![]() #15Michigan 9-278% +10½ -118SugarHouse | |||||||
![]() #22Pittsburgh 8-373% +7½ -120SugarHouse | |||||||
Central Michigan 7-483% +10½ -114Caesars | |||||||
Miami (OH) 6-5100% -17½ -109Caesars | |||||||
![]() Kansas State 5-614% -17 -110Bet365 | |||||||
Baylor 5-637% -2½ -114Caesars | |||||||
Oklahoma State 1-10100% +14½ -118FanDuel | |||||||
![]() Delaware 5-60% -4 -110Bet365 | |||||||
![]() Sam Houston State 2-983% +10½ -122FanDuel | |||||||
#11Brigham Young 10-188% -17½ -110FanDuel | |||||||
Marshall 5-625% -7 -110Bet365 | |||||||
![]() Old Dominion 8-325% -27 -110Bet365 | |||||||
![]() Missouri State 7-412% -2½ -112BetRivers | |||||||
![]() Jacksonville State 7-440% +3 -115BetMGM | |||||||
Appalachian State 5-650% -2½ -109Caesars | |||||||
Syracuse 3-814% +3½ -122FanDuel | |||||||
![]() Tulsa 4-70% -8½ -110Bet365 | |||||||
Texas State 5-650% -8½ -114FanDuel | |||||||
![]() Louisiana 5-60% -8½ -113SugarHouse | |||||||
New Mexico State 4-733% -3½ -117SugarHouse | |||||||
#19Tennessee 8-333% -2½ -110Bet365 | |||||||
![]() Duke 6-567% +1½ -118FanDuel | |||||||
Rutgers 5-6100% +14 -118BetRivers | |||||||
![]() #8Oklahoma 9-277% -10 -107Caesars | |||||||
![]() UTSA 6-533% -6½ -120FanDuel | |||||||
TCU 6-495% -3½ -107Caesars | |||||||
Southern Miss 7-480% -6 -120SugarHouse | |||||||
![]() Arkansas 2-992% +3 -113Caesars | |||||||
Minnesota 6-515% +1½ -114FanDuel | |||||||
![]() Washington 8-388% +7 -113BetRivers | |||||||
![]() Liberty 4-771% +2½ -112Caesars | |||||||
![]() Coastal Carolina 6-578% +21½ -105FanDuel | |||||||
Florida 3-80% -½ -115SugarHouse | |||||||
![]() Washington State 5-633% -13½ -105FanDuel | |||||||
![]() South Florida 8-30% -27½ -117SugarHouse | |||||||
Michigan State 3-899% -3½ -114FanDuel | |||||||
![]() #18Virginia 9-225% -9 -117SugarHouse | |||||||
![]() North Carolina State 6-520% -7½ -108Caesars | |||||||
Auburn 5-698% +6 -110BetMGM | |||||||
#24Tulane 9-20% -29½ -115BetMGM | |||||||
Illinois 7-415% -6½ -115Bet365 | |||||||
#17USC 8-229% -21½ -110FanDuel | |||||||
![]() California 6-536% +13½ -110BetMGM | |||||||
![]() Nevada 3-887% +7½ -105BetMGM | |||||||
![]() San Jose State 3-883% +3½ -115Caesars | |||||||
Stanford 4-773% +32½ -110Bet365 | |||||||
![]() Hawaii 7-414% -7½ -113BetRivers | |||||||
![]() Massachusetts 0-1214 +14½ -110Bet365 | |||||||
Eastern Michigan 4-821 +10 -105BetMGM |
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