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The upcoming Saturday football game on November 15, 2025, between the Virginia Cavaliers and Duke Blue Devils at Brooks Field at Wallace Wade Stadium in Durham, NC, promises an exciting clash in the 2025-26 NCAAF season. The Virginia Cavaliers, coming off an 8-2 record and a solid 6-4 ATS performance, face the Duke Blue Devils, who hold a 5-4 record with a 4-5 ATS. Virginia's offense, led by their starting quarterback, boasts 243.5 passing yards and 184.3 rushing yards per game, while Duke's offense averages 312.9 passing yards and 139.6 rushing yards. Defensively, Duke's pass rush and sack rates present a challenge to Virginia's passing game, but Virginia's defense also stands strong against the run and pass.
The point spread for this game is Duke favored by 4.5 points, with a total points over/under set at 58.5. This suggests a moderately high-scoring game with Duke expected to edge out a win. The starting quarterbacks for both teams are key players to watch, with Duke's quarterback offering a slight passing offense advantage, while Virginia's balanced attack could keep the game competitive. The game will be broadcast on ESPN2, making it accessible for fans and bettors nationwide.
Betting trends and game insights reveal that Duke has struggled ATS at home with a 1-3 record, while Virginia has been more consistent on the road with a 2-2 ATS record. This matchup also recalls their last meeting on November 18, 2023, where Virginia narrowly defeated Duke 30-27, showcasing the competitive nature of this rivalry. Bettors should consider these factors alongside the current odds and team performances to make informed wagers.
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#20Louisville 7-229% -1½ -115BetMGM | |||||||
![]() #8Oregon 8-134% -24½ -115BetMGM | |||||||
![]() Connecticut 7-322% -7½ -105FanDuel | |||||||
![]() Charlotte 1-8100% +18½ -110FanDuel | |||||||
![]() #25Cincinnati 7-218% -6 -110Bet365 | |||||||
Navy 7-223% +10½ -114BetRivers | |||||||
![]() #2Indiana 10-016% -29 -112Caesars | |||||||
![]() #22Pittsburgh 7-270% +12½ -110Caesars | |||||||
Ball State 4-585% +2½ -106Caesars | |||||||
Oklahoma State 1-869% +20 -117SugarHouse | |||||||
#3Texas A&M 9-072% -17½ -110FanDuel | |||||||
![]() Northwestern 5-445% +11½ -115BetMGM | |||||||
LSU 5-419% -5 -110Caesars | |||||||
![]() Tulsa 2-740% +2½ -106FanDuel | |||||||
![]() Arizona State 6-312% -11 -114SugarHouse | |||||||
Kentucky 4-5- -21½ -110Bet365 | |||||||
Georgia State 1-876% +8 -112BetRivers | |||||||
UAB 3-678% +18½ -115FanDuel | |||||||
![]() New Mexico 6-317% -14 -115BetRivers | |||||||
![]() Missouri State 6-30% -4½ -105FanDuel | |||||||
![]() James Madison 8-170% -21 -109Caesars | |||||||
![]() Boston College 1-949% +17 -117SugarHouse | |||||||
![]() Duke 5-449% -4½ -110Caesars | |||||||
![]() #15Miami (FL) 7-26% -14½ -113BetRivers | |||||||
Michigan State 3-677% +7½ -114FanDuel | |||||||
#4Alabama 8-112% -5½ -113BetRivers | |||||||
Southern Miss 7-236% -3 -110BetMGM | |||||||
![]() #6Texas Tech 9-187% -23½ -110BetMGM | |||||||
![]() Louisiana-Monroe 3-667% +4½ -105FanDuel | |||||||
Illinois 6-318% -15 -113BetRivers | |||||||
#17USC 7-224% -6 -117SugarHouse | |||||||
![]() Western Kentucky 7-20% -13 -121SugarHouse | |||||||
![]() Nevada 1-892% +9½ +102Caesars | |||||||
East Carolina 6-373% -2½ -120SugarHouse | |||||||
Tulane 7-225% -17½ -110Caesars | |||||||
#23Tennessee 6-31% -39½ -110BetMGM | |||||||
![]() Wake Forest 6-342% -5½ -115BetRivers | |||||||
![]() Florida International 4-575% +3 -118BetRivers | |||||||
![]() Georgia Southern 4-540% -3 -114Caesars | |||||||
![]() Sam Houston State 1-885% +10½ -110Bet365 | |||||||
Baylor 5-482% +9 -114BetRivers | |||||||
![]() #7Ole Miss 9-118% -11½ -105BetMGM | |||||||
![]() Washington 6-39% -16½ -110Bet365 | |||||||
UNLV 7-212% -6 -110Bet365 | |||||||
![]() #5Georgia 8-168% -6 -110Bet365 | |||||||
Florida State 4-515% -13½ -115BetRivers | |||||||
![]() #1Ohio State 9-036% -31½ -105Bet365 | |||||||
![]() Missouri 6-327% -6½ -118FanDuel | |||||||
![]() Jacksonville State 6-375% +3½ -118FanDuel | |||||||
![]() Washington State 4-58% -7½ -115Bet365 | |||||||
#12Brigham Young 8-111% -3 -110Bet365 | |||||||
![]() Fresno State 6-329% -3½ -105BetMGM | |||||||
San Diego State 7-237% -1½ -112FanDuel | |||||||
![]() Akron 4-735 -7 -118SugarHouse | |||||||
![]() Western Michigan 6-417 +2 -139SugarHouse | |||||||
![]() Massachusetts 0-103 +10 -110BetMGM | |||||||
Miami (OH) 5-53 +5½ -105Bet365 | |||||||
Central Michigan 6-438 -2½ -110BetMGM | |||||||
![]() Old Dominion 7-333 -9 -115BetRivers |
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