Wake Forest Demon Deacons vs Duke Blue Devils Picks

The Saturday football showdown on November 29, 2025, features the Wake Forest Demon Deacons visiting the Duke Blue Devils at Brooks Field at Wallace Wade Stadium in Durham, NC. This exciting NCAAF Week 14 matchup is set to be broadcast on the ACC Network, making it a can't-miss event for college football fans and sports bettors alike.

Our picks for this game lean towards Duke with a predicted score of 30 to 26. Duke is favored on the point spread at -1, boasting a 56.5% cover rate and a solid 4.2% expected value (EV), indicating a profitable betting opportunity. Wake Forest, while competitive, trails with a 44.4% cover rate on the spread. This aligns well with our betting tips, suggesting Duke has the edge in both performance and betting value.

In the last 10 games, our prediction model has excelled in the 2-way (including overtime) market, with Duke winning 6 out of 10, demonstrating a strong hit rate of 63.2%. This track record supports our confidence in Duke's chances to cover the spread in this key ACC clash. Bettors can use these insights to make informed decisions and potentially boost their returns.

For those looking to dive deeper into NCAAF betting, check out our comprehensive ACC picks and predictions for more expert analysis. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.