Betting Trends: Penn Quakers vs Harvard Crimson

The upcoming NCAAF Week 12 matchup on November 15, 2025, features the Penn Quakers visiting the Harvard Crimson at Harvard Stadium in Allston, MA. This Saturday football game promises exciting betting trends as both teams bring contrasting strengths to the field. Harvard Crimson boasts a potent offensive attack averaging 457.9 total yards per game, led by their starting quarterback who manages a balanced pass offense of 275.9 yards and a solid run game. Defensively, Harvard is strong against the pass, allowing just 173.8 yards per game, which could challenge Penn's 234.5 passing yards on offense.

Penn Quakers, on the other hand, have a stout defense allowing 231.3 passing yards and 143.8 rushing yards per game, but their offensive line faces pressure from Harvard's effective pass rush. Penn’s offense averages 379.1 total yards per game, with their starting quarterback expected to play and bring a competitive edge. The point spread and total points are yet to be released, but the previous close game between these teams on November 16, 2024, saw Harvard win 31-28 in a high-scoring affair over 53.5 points, indicating a potentially tight and thrilling contest.

Harvard’s strong home record and unbeaten straight-up record at home make them favorites, but Penn’s resilience and recent performances suggest this will be a close battle. Bettors should consider these betting insights and game stats when placing wagers. The game will be broadcast on ESPN+, providing ample opportunity to catch the action live. For those looking to gain an edge, Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

In their last matchup on November 16, 2024, which Harvard won 31-28, the Crimson narrowly defeated the Quakers, highlighting the competitive nature of this rivalry. Check out the latest odds and team updates to make an informed betting decision.