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The upcoming Saturday football game on November 22, 2025, between the Houston Cougars and TCU Horned Frogs at TDECU Stadium in Houston, TX, is shaping up to be a thrilling NCAAF regular season matchup. Bettors should pay close attention to the injury report as it can significantly impact the game's outcome and betting lines.
Houston enters the game with several key players sidelined. Wide Receiver Devan Williams is out with an undisclosed injury and is not expected to return until November 29, 2025. Tight End Traville Frederick is questionable, while other players like Tight End Jayden York, Running Back Re'Shaun Sanford, Wide Receiver Stephon Johnson, and Offensive Lineman David Ndukwe are officially out for the season due to various injuries, including surgery and knee issues. These absences could weaken Houston's offensive capabilities, particularly in the passing game and blocking schemes.
On the other side, TCU Horned Frogs also face notable injuries. Cornerback Elijah Jackson and Kicker Kyle Lemmermann are out, with multiple wide receivers including Dozie Ezukanma, Jacobe Hayes, and Ed Small also sidelined. Running Back Trent Battle is probable, but the team will be missing depth on defense and special teams. These injuries may affect TCU's defensive resilience and scoring opportunities.
Understanding these player statuses is crucial for making informed bets. Injuries to core players can shift the balance of the game, influencing point spreads and totals. For more detailed injury updates, bettors should visit the NCAAF injury list page NCAAF injury updates. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your wager with a U.S. regulated sportsbook and capitalize on the edge.
![]() #1Ohio State 10-032% -31 -115BetRivers | |||||||
Army 5-423% -9½ -118FanDuel | |||||||
![]() Wake Forest 7-333% -17½ -110Caesars | |||||||
Virginia Tech 3-725% +18 -109Caesars | |||||||
![]() #8Oklahoma 8-235% -5½ -110Bet365 | |||||||
SMU 7-354% -3½ -117SugarHouse | |||||||
![]() Iowa State 6-434% -3½ -105BetMGM | |||||||
![]() Northwestern 5-541% -3½ -110BetMGM | |||||||
#3Texas A&M 10-0- -54½ -110Bet365 | |||||||
![]() #4Georgia 9-163% -43½ -112Caesars | |||||||
![]() Georgia Southern 5-555% +11 -115SugarHouse | |||||||
![]() James Madison 9-149% -13½ -120FanDuel | |||||||
![]() Arizona 7-331% -6½ -114Caesars | |||||||
![]() Toledo 6-469% -27½ -110Bet365 | |||||||
Wyoming 4-626% -6½ -112Caesars | |||||||
![]() Kennesaw State 7-321% -6½ -105FanDuel | |||||||
Auburn 4-6- -27½ -110Bet365 | |||||||
#10Alabama 8-2- -50½ -107Caesars | |||||||
Appalachian State 4-673% +5½ -115Caesars | |||||||
![]() Florida Atlantic 4-684% +7½ -120FanDuel | |||||||
![]() UTEP 2-824% -3 -113Caesars | |||||||
![]() Middle Tennessee 1-950% -6½ -113BetRivers | |||||||
![]() Louisiana Tech 5-524% +1½ -115FanDuel | |||||||
UAB 3-773% +21½ -109Caesars | |||||||
![]() North Carolina 4-671% +7 -115BetMGM | |||||||
![]() #17Texas 7-313% -8 -115BetRivers | |||||||
![]() #7Oregon 9-160% -10 -110Bet365 | |||||||
Iowa 6-459% -16½ -110Bet365 | |||||||
![]() UTSA 5-567% +2½ -108Caesars | |||||||
![]() #14Vanderbilt 8-217% -8 -115SugarHouse | |||||||
![]() South Alabama 3-757% +1½ -115BetMGM | |||||||
![]() Florida International 5-560% -1 -115Bet365 | |||||||
#9Notre Dame 8-272% -35 -110Bet365 | |||||||
Temple 5-584% +9½ -105FanDuel | |||||||
UCF 4-622% -13 -110Bet365 | |||||||
Maryland 4-674% +14 -107Caesars | |||||||
![]() #23Houston 8-228% -1 -113BetRivers | |||||||
![]() #12Utah 8-269% -15½ -125BetMGM | |||||||
Troy 6-423% -9½ -118FanDuel | |||||||
![]() South Carolina 3-759% -23½ -122FanDuel | |||||||
![]() Clemson 5-5- -41½ -110Caesars | |||||||
Texas State 4-629% -19½ -110Bet365 | |||||||
![]() #16Georgia Tech 9-117% -2½ -110Bet365 | |||||||
![]() Penn State 4-634% -7½ -113BetRivers | |||||||
![]() Boise State 6-40% -16½ -110Bet365 | |||||||
Air Force 3-789% +4 -120SugarHouse | |||||||
Florida 3-788% +4½ -112BetRivers | |||||||
Stanford 3-781% +3½ -113Caesars | |||||||
![]() Wisconsin 3-757% +8½ -110BetMGM | |||||||
Rice 5-588% +18½ -112BetRivers | |||||||
LSU 6-48% -21½ -110Bet365 | |||||||
![]() Cincinnati 7-338% +3 -113Caesars | |||||||
![]() Colorado 3-785% +7½ -115Bet365 | |||||||
UCLA 3-790% +10½ -110Bet365 | |||||||
San Diego State 8-211% -11½ -114FanDuel | |||||||
![]() Fresno State 7-317% -2½ -115Bet365 | |||||||
![]() Ohio 7-442 -33½ -115BetRivers | |||||||
Bowling Green 3-816 -2½ -110Bet365 | |||||||
![]() Northern Illinois 3-819 +7½ -122FanDuel | |||||||
Buffalo 5-620 +2½ -107Caesars | |||||||
![]() Kent State 4-716 +8½ -115FanDuel | |||||||
Arkansas State 5-630 -2½ -110Bet365 | |||||||
![]() North Carolina State 6-521 +7 -118SugarHouse | |||||||
UNLV 9-238 -2 -121SugarHouse |
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