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The upcoming clash on December 6, 2025, between the Indiana Hoosiers and Ohio State Buckeyes at Lucas Oil Stadium in Indianapolis, IN, promises an exciting showdown in the 2025-26 NCAAF season. This Saturday football game is set to captivate fans and bettors alike, broadcasting live on Fox.
Current odds show the Buckeyes as favorites with a point spread of -4½ -108, while the Hoosiers are underdogs at +4½ -112. Opening odds had the Buckeyes at -4 -110, indicating a slight shift in the betting lines that bettors should consider when placing their wagers. The over/under total is set at 47½ with odds of -117 for the over and -104 for the under, offering additional betting opportunities.
Understanding these odds and the movement from the opening lines provides valuable insight into market sentiment and potential game outcomes. Bettors can leverage this information to make informed decisions, whether they're eyeing the point spread or totals market. For the latest NCAAF odds, explore our comprehensive NCAAF odds page.
Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. The best moneyline odds available are +168 for Indiana at Caesars and -205 for Ohio State also at Caesars.
This matchup at Lucas Oil Stadium offers a great opportunity to capitalize on shifting betting odds and enjoy thrilling Saturday football action. Stay informed and make your betting strategy count!
![]() Jacksonville State 8-447% +2½ -108BetRivers | |||||||
![]() #25James Madison 11-127% -23 -113BetRivers | |||||||
#20Tulane 10-262% +2½ -105Caesars | |||||||
![]() Boise State 8-429% -3½ -120BetMGM | |||||||
![]() #4Texas Tech 11-129% -12½ -110Bet365 | |||||||
![]() Western Michigan 8-437% -1½ -114FanDuel | |||||||
#9Alabama 10-240% +3 -121BetRivers | |||||||
![]() #17Virginia 10-219% -3½ -105BetMGM | |||||||
![]() #1Ohio State 12-049% -3½ -125SugarHouse |
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