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The upcoming Friday football game on November 28, 2025, between the Indiana Hoosiers and Purdue Boilermakers at Ross-Ade Stadium in West Lafayette, IN, is set to be a thrilling NCAAF matchup. Fans and bettors alike will want to tune in to NBC for the live broadcast of this exciting clash.
Our expert picks for Indiana Hoosiers vs Purdue Boilermakers suggest a strong performance by the Indiana Hoosiers, with a predicted score of 41 to 15, favoring Indiana on the moneyline. The over/under total is predicted at 56.2 points, with a slight edge towards the over 52.5 market, which has shown a 55.3% cover percentage and a positive EV of 2.9% in recent games. This indicates a valuable betting opportunity for those interested in totals betting.
In recent matchups, our prediction model has been profitable in the last 10 games, winning 6 of them on the point spread market, particularly with Purdue +28.5 showing a 54.7% hit rate and a 3.5% EV. This solid track record helps bettors make informed decisions and capitalize on favorable odds.
For those looking to dive deeper into NCAAF betting, we recommend exploring our comprehensive league picks page for more insights and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
West Virginia 4-773% +24½ -130BetMGM | |||||||
![]() Florida Atlantic 4-782% +7 -105BetMGM | |||||||
Louisville 7-415% -2½ -110Bet365 | |||||||
![]() South Carolina 3-732% -2½ -110Bet365 | |||||||
![]() #15Michigan 9-273% +10½ -122FanDuel | |||||||
![]() #22Pittsburgh 8-363% +7 -110Caesars | |||||||
Central Michigan 7-454% +11½ -115FanDuel | |||||||
Miami (OH) 6-550% -17½ -105Bet365 | |||||||
![]() Kansas State 5-635% -17 -110Bet365 | |||||||
Baylor 5-643% -2½ -114Caesars | |||||||
Oklahoma State 1-1081% +14 -110BetMGM | |||||||
![]() Delaware 5-630% -3½ -118FanDuel | |||||||
![]() Sam Houston State 2-971% +11½ -113BetRivers | |||||||
#11Brigham Young 10-166% -17½ -106FanDuel | |||||||
Marshall 5-622% -10 -110Bet365 | |||||||
![]() Old Dominion 8-327% -27½ -110Bet365 | |||||||
![]() Missouri State 7-429% -2½ -110Bet365 | |||||||
![]() Jacksonville State 7-427% +3 -115BetMGM | |||||||
Appalachian State 5-643% -1½ -102FanDuel | |||||||
Syracuse 3-840% +3 -108BetRivers | |||||||
![]() Tulsa 4-745% -8½ -110Bet365 | |||||||
Texas State 5-640% -8½ -115FanDuel | |||||||
![]() Louisiana 5-620% -8½ -114SugarHouse | |||||||
New Mexico State 4-767% -3½ -105BetMGM | |||||||
#19Tennessee 8-336% -2½ -112FanDuel | |||||||
![]() Duke 6-546% -1 -110Bet365 | |||||||
Rutgers 5-694% +14 -118BetRivers | |||||||
![]() #8Oklahoma 9-264% -10½ -110Bet365 | |||||||
![]() UTSA 6-537% -7 -120SugarHouse | |||||||
TCU 6-487% -3 -124BetRivers | |||||||
Southern Miss 7-450% -6 -118SugarHouse | |||||||
![]() Arkansas 2-980% +4 -112Caesars | |||||||
Minnesota 6-534% +2½ -115Caesars | |||||||
![]() Washington 8-373% +7 -110Bet365 | |||||||
![]() Liberty 4-779% +2½ -115SugarHouse | |||||||
![]() Coastal Carolina 6-587% +22 -109Caesars | |||||||
Florida 3-827% -½ -115SugarHouse | |||||||
![]() Washington State 5-647% -13 -115BetRivers | |||||||
![]() South Florida 8-35% -28 -107Caesars | |||||||
Michigan State 3-895% -3½ -114FanDuel | |||||||
![]() #18Virginia 9-219% -8 +100Bet365 | |||||||
![]() North Carolina State 6-524% -7 -110Caesars | |||||||
Auburn 5-682% +6 -113BetRivers | |||||||
#24Tulane 9-28% -29½ -115BetMGM | |||||||
Illinois 7-413% -7 -110Bet365 | |||||||
#17USC 8-242% -21½ -108FanDuel | |||||||
![]() California 6-548% +13½ -110Bet365 | |||||||
![]() Nevada 3-874% +7½ -110Bet365 | |||||||
![]() San Jose State 3-886% +3½ -109Caesars | |||||||
Stanford 4-778% +32½ -110BetMGM | |||||||
![]() Hawaii 7-417% -7½ -110Caesars | |||||||
![]() Massachusetts 0-1214 +14½ -110Bet365 | |||||||
Eastern Michigan 4-821 +10 -105BetMGM | |||||||
![]() Memphis 8-417 -3½ -112Caesars | |||||||
Buffalo 5-726 +7½ -120FanDuel | |||||||
![]() Mississippi State 5-719 +8 -127SugarHouse | |||||||
Nebraska 7-516 +6 +100Caesars | |||||||
![]() Northern Illinois 3-931 -4½ -115Bet365 | |||||||
![]() Kansas 5-721 +10½ -115Caesars | |||||||
![]() Colorado State 2-1021 +2½ -105FanDuel | |||||||
![]() #23Georgia Tech 9-39 +16½ -105BetMGM | |||||||
![]() New Mexico 9-323 +1½ -115BetMGM | |||||||
![]() North Texas 11-152 -20 -112SugarHouse | |||||||
![]() Utah State 6-624 +1½ -105FanDuel | |||||||
![]() #16Texas 9-327 +2½ +100Caesars | |||||||
![]() Purdue 2-103 +29 -113BetRivers | |||||||
![]() #20Arizona State 8-47 +2 -107Caesars |
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