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Nov 28, 2025 7:30 PM EST
Week 14
IND
-28½ (-105)o54 (-110)
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Indiana Hoosiers vs Purdue Boilermakers Picks
Updated:Nov 24, 2025 1:50 AM EST
The upcoming Friday football game on November 28, 2025, features an exciting NCAAF regular season Week 14 matchup between the Purdue Boilermakers and the Indiana Hoosiers at Ross-Ade Stadium in West Lafayette, IN. This game promises to be a thrilling contest as both teams battle for supremacy in the Big Ten Conference. Fans can catch the action live on NBC, making it a perfect event for football enthusiasts and bettors alike.
Our picks favor the Indiana Hoosiers with a predicted score of 41 to Purdue's 16, including a recommended spread bet on Indiana at -28.5. This prediction is backed by a strong 94.2% coverage percentage and an expected value (EV) of -4.6%, indicating a confident edge for Indiana in this contest. Additionally, the total points are expected to go over 52.5, with a predicted total score of approximately 56.9 points.
Our prediction model has been profitable in the last 10 games, with a particularly high hit rate in the 2-way market, winning 6 out of 10 times. This insight is valuable for bettors looking to make informed decisions. The Indiana Hoosiers have demonstrated consistency, and the current betting trends and stats suggest that they are the best bet for this game.
For more expert picks and predictions, check out our comprehensive NCAAF picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
Total
PURSpread
CONSENSUS LINE
+28½ (-112)
PROJECTION
PUR (16) - IND (41)
COVER PROBABILITY
EXPECTED VALUE
+2.3%
BET RATING
SEASON COVER %
4/11
36%
NCAAF
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NCAAF Week 14
NCAAF Tue 11/25
 Massachusetts 0-1180% +14½ -110Bet365 | |||||||
 Eastern Michigan 4-767% +6½ -110Bet365 | |||||||
 Memphis 8-320% -5½ -107Caesars | |||||||
 Buffalo 5-650% +6½ -110BetMGM | |||||||
 Mississippi State 5-688% +7½ -110BetMGM | |||||||
 Nebraska 7-489% +5½ -110BetMGM | |||||||
 Northern Illinois 3-8- -4½ -112FanDuel | |||||||
 Kansas 5-660% +13½ -106FanDuel | |||||||
 Colorado State 2-90% +3½ -120FanDuel | |||||||
 #16Georgia Tech 9-275% +13 -105BetMGM | |||||||
 New Mexico 8-3100% +2½ -115FanDuel | |||||||
 North Texas 10-120% -19½ -110Bet365 | |||||||
 Utah State 6-5100% +3½ -122FanDuel | |||||||
 #17Texas 8-371% +2½ -104FanDuel | |||||||
 Purdue 2-980% +28½ -110BetMGM | |||||||
 #25Arizona State 8-336% +1½ -110Caesars | |||||||
 West Virginia 4-7100% +21½ -122FanDuel | |||||||
 Florida Atlantic 4-775% +6½ -110Bet365 | |||||||
 Louisville 7-40% -3½ -105FanDuel | |||||||
 South Carolina 3-760% -2 -110Bet365 | |||||||
 #18Michigan 9-275% +10½ -115FanDuel | |||||||
 Pittsburgh 8-333% +6½ -102FanDuel | |||||||
 Central Michigan 7-450% +10½ -110BetMGM | |||||||
 Miami (OH) 6-5- -17½ -110Bet365 | |||||||
 Kansas State 5-633% -17 -110Bet365 | |||||||
 Baylor 5-667% -2 -113BetRivers | |||||||
 Oklahoma State 1-10- +14 -110BetMGM | |||||||
 Delaware 5-60% -5 -110Bet365 | |||||||
 Sam Houston State 2-9- +10½ -110FanDuel | |||||||
 #11Brigham Young 10-10% -17½ -110Bet365 | |||||||
 Marshall 5-60% -7 -110Bet365 | |||||||
 Old Dominion 8-3100% -26½ -110BetMGM | |||||||
 Missouri State 7-450% -3 -110Bet365 | |||||||
 Jacksonville State 7-40% +2½ -110Caesars | |||||||
 Appalachian State 5-6100% -2½ -109Caesars | |||||||
 Syracuse 3-8- +3½ -122FanDuel | |||||||
 Tulsa 4-70% -8½ -110Bet365 | |||||||
 Texas State 5-60% -7½ -115FanDuel | |||||||
 Louisiana 5-6- -11½ -109Caesars | |||||||
 New Mexico State 4-7- -4½ -110Bet365 | |||||||
 #20Tennessee 8-327% -2 -114BetRivers | |||||||
 Duke 6-5100% -2½ -110Bet365 | |||||||
 Rutgers 5-6100% +11½ -110BetRivers | |||||||
 #8Oklahoma 9-221% -10 -107Caesars | |||||||
 UTSA 6-533% -6½ -110BetMGM | |||||||
 TCU 6-40% -4 -110Bet365 | |||||||
 Southern Miss 7-467% -6½ -120FanDuel | |||||||
 Arkansas 2-9100% +2½ -104FanDuel | |||||||
 Minnesota 6-50% -1½ -107Caesars | |||||||
 Washington 8-374% +7 -110BetMGM | |||||||
 Liberty 4-750% +2½ -105FanDuel | |||||||
 Coastal Carolina 6-5100% +22½ -110Bet365 | |||||||
 Florida 3-80% -2 -105Bet365 | |||||||
 Washington State 5-633% -13½ -110Bet365 | |||||||
 South Florida 8-30% -25½ -110BetMGM | |||||||
 Michigan State 3-850% -3½ -110BetRivers | |||||||
 #19Virginia 9-233% -10½ -110Bet365 | |||||||
 North Carolina State 6-533% -7 -110Bet365 | |||||||
 Auburn 5-6100% +5½ -110Caesars | |||||||
 #24Tulane 9-2- -29 -109BetRivers | |||||||
 #21Illinois 7-40% -6½ -113BetRivers | |||||||
 #15USC 8-2100% -20½ -110Bet365 | |||||||
 California 6-5100% +12½ -109Caesars | |||||||
 Nevada 3-8100% +8½ -110Bet365 | |||||||
 San Jose State 3-8100% +2½ -108FanDuel | |||||||
 Stanford 4-7100% +32½ -108Caesars | |||||||
 Hawaii 7-40% -10 -110Bet365 |
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