Nov 29, 2025 12:00 PM EST

Week 14

5-6

Kentucky

7-4

Louisville

LOU

-3½ (-110)o47½ (-110)

ESPN Networks, ACC Network, 612

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Louisville Cardinals vs Kentucky Wildcats Betting Trends

Updated:Nov 24, 2025 1:13 AM EST

The upcoming showdown on November 29, 2025, between the Louisville Cardinals and Kentucky Wildcats at L&N Federal Credit Union Stadium in Louisville, KY, promises an exciting chapter in the 2025-26 NCAAF season. Fans can catch this thrilling Saturday football game on ESPN Networks and ACC Network, making it a must-watch event for college football enthusiasts.

Kentucky Wildcats enter the game with a mixed recent record, having lost to Vanderbilt 17-45 but securing solid victories against Tennessee Tech, Florida Gators, and Auburn Tigers. Louisville Cardinals, on the other hand, have had a challenging season with narrow wins and losses, including a recent 6-38 defeat against SMU Mustangs. The Cardinals are favored by 3.5 points with a total points line set at 47.5, suggesting a moderately low-scoring affair.

Quarterback analysis reveals that both teams rely on starting quarterbacks who have shown resilience despite some injury concerns. Kentucky's passing offense, averaging 211.2 yards, faces a Louisville pass defense allowing about 198.8 yards per game, while Louisville's offense, averaging 230.3 yards, will challenge Kentucky's stout defense that limits opponents to 245.2 yards. The battle in the trenches will be key, with Kentucky's pass rush and run defense slightly better than Louisville's, impacting passing protection and run game effectiveness.

Betting trends indicate Kentucky's ATS record stands at 5-6 overall, with Louisville struggling at 3-8 ATS, especially at home where they are 0-7. These betting stats combined with the current odds favor Louisville as the favorite but suggest a tight contest. Bettors should consider the under 47.5 points line based on recent scoring trends and defensive strengths.

In their last matchup on November 30, 2024, Kentucky dominated Louisville 41-14 at Kroger Field, a reminder of the Wildcats' potential to control the game. For a deeper dive into the betting trends and to place smarter wagers, Start your OddsTrader Turbo subscription or place your bet with a U.S. regulated sportsbook and profit off the edge.

What is the point spread for the Louisville Cardinals vs Kentucky Wildcats matchup?

ATS Records

Kentucky

Louisville

All

All
1st half
2nd half
1st quarter
2nd quarter
3rd quarter
4th quarter

5-6 (160th)Against the Spread3-8 (253rd)

5-6 (158th)Straight Up7-4 (92nd)

-0.9Straight Up Units+0.4

8-3Over / Under5-6

TEAM MATCHUP

Kentucky

Louisville

OFF

DEF

OFF

DEF

25.1Points29.2

359.4Total Yards384.2

5.4Yards Per Play5.9

211.2Passing Yards230.3

19.6 - 31.1 (63.2%)Completions-Attempts21.8 - 33.9 (64.3%)

6.8Yards Per Passing Play6.8

12.5Sacks-Yards Lost14.5

148.2Rushing Yards153.9

36.9Attempts30.5

4Yards Per Rush5.1

20.61st Downs19

10.3Passing9.9

8.5Rushing7.5

1.8Penalties1.6

5.6 / 13.2 (42.8%)3rd Down4.9 / 13.3 (37%)

1 / 1.8 (55%)4th Down0.4 / 0.8 (44.4%)

2.5 / 3.3 (77.8%)Red Zone2.6 / 2.9 (90.6%)

4.9 (39.8)Penalties (Yards)6.8 (63.5)

1.1Interceptions0.8

0.8Fumbles Lost0.6

70.1Total Plays66.4

5.3Kickoffs6.2

1.1Returns1.5

20.5Yards33

18.8Yards Per Return22.7

4Punts4.5

1.2Returns2

4.8Yards39.4

4.1Yards Per Return19.7

HEAD TO HEAD

Kentucky

Louisville

LOU

NCAAF

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

Spread

Spread
Money
Total
Merged

Game

Game
1H
2H
1Q
2Q
3Q
4Q

This Week

Last Week

NCAAF Tue 11/25

Personalize your notifications and get updates on the teams, players or events you care about most. TUE 11/254:30 PM Bowling Green 3-8 20% -14½ -108Caesars
Massachusetts 0-11 80% +14½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. TUE 11/257:30 PM Western Michigan 7-4 33% -6½ -107Caesars
Eastern Michigan 4-7 67% +6½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/277:30 PM Navy 8-2 80% +5½ -105BetMGM
Memphis 8-3 20% -5½ -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/2812:00 PM Ohio 7-4 50% -6 -110Bet365
Buffalo 5-6 50% +6½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/2812:00 PM #6Ole Miss 10-1 12% -7 -115Bet365
Mississippi State 5-6 88% +7½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/2812:00 PM Iowa 7-4 11% -5 -110Bet365
Nebraska 7-4 89% +5½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/2812:00 PM Kent State 4-7 - +5½ -110BetRivers
Northern Illinois 3-8 - -4½ -112FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/2812:00 PM #12Utah 9-2 40% -13½ -110Caesars
Kansas 5-6 60% +13½ -106FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/283:00 PM Air Force 3-8 100% -3 -109Caesars
Colorado State 2-9 0% +3½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/283:30 PM #4Georgia 10-1 25% -12½ -113BetRivers
#16Georgia Tech 9-2 75% +13 -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/283:30 PM San Diego State 9-2 0% -1½ -110Bet365
New Mexico 8-3 100% +2½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/283:30 PM Temple 5-6 80% +19½ -108Caesars
North Texas 10-1 20% -19½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/284:00 PM Boise State 7-4 0% -3 -110BetMGM
Utah State 6-5 100% +3½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/287:30 PM #3Texas A&M 11-0 29% -2½ -110Bet365
#17Texas 8-3 71% +2½ -104FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/287:30 PM #2Indiana 11-0 20% -28 -110Bet365
Purdue 2-9 80% +28½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/289:00 PM Arizona 8-3 64% -1 -110Bet365
#25Arizona State 8-3 36% +1½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM #5Texas Tech 10-1 0% -20½ -115BetMGM
West Virginia 4-7 100% +21½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM East Carolina 7-4 25% -6½ -108FanDuel
Florida Atlantic 4-7 75% +6½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM Kentucky 5-6 100% +3½ -110Bet365
Louisville 7-4 0% -3½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM Clemson 6-5 40% +2½ -110BetMGM
South Carolina 3-7 60% -2 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM #1Ohio State 11-0 25% -9½ -113BetRivers
#18Michigan 9-2 75% +10½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM #13Miami (FL) 9-2 67% -6½ -110Bet365
Pittsburgh 8-3 33% +6½ -102FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM Toledo 7-4 50% -9½ -112BetRivers
Central Michigan 7-4 50% +10½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM Ball State 4-7 - +18½ -114FanDuel
Miami (OH) 6-5 - -17½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM Colorado 3-8 67% +17½ -110BetRivers
Kansas State 5-6 33% -17 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM #23Houston 8-3 33% +2½ -110BetMGM
Baylor 5-6 67% -2 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2912:00 PM Iowa State 7-4 - -13½ -113BetRivers
Oklahoma State 1-10 - +14 -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/291:00 PM UTEP 2-9 100% +5½ -110FanDuel
Delaware 5-6 0% -5 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/291:00 PM Florida International 6-5 - -10 -110Bet365
Sam Houston State 2-9 - +10½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/291:00 PM UCF 5-6 100% +18½ -112FanDuel
#11Brigham Young 10-1 0% -17½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/291:30 PM Georgia Southern 5-6 100% +7½ -120FanDuel
Marshall 5-6 0% -7 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/292:00 PM Georgia State 1-9 0% +26½ -105Bet365
Old Dominion 8-3 100% -26½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/292:00 PM Louisiana Tech 6-5 50% +3½ -114BetRivers
Missouri State 7-4 50% -3 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/292:00 PM Western Kentucky 8-3 100% -2½ -110Caesars
Jacksonville State 7-4 0% +2½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/292:30 PM Arkansas State 5-6 0% +2½ -110Caesars
Appalachian State 5-6 100% -2½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:00 PM Boston College 1-10 - -3 -108Caesars
Syracuse 3-8 - +3½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:00 PM UAB 3-8 100% +8½ -105FanDuel
Tulsa 4-7 0% -8½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:00 PM South Alabama 4-7 100% +9½ -110Bet365
Texas State 5-6 0% -7½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:00 PM Louisiana-Monroe 3-8 - +12½ -115FanDuel
Louisiana 5-6 - -11½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:00 PM Middle Tennessee 2-9 - +5½ -110BetMGM
New Mexico State 4-7 - -4½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM #14Vanderbilt 9-2 73% +2½ -109Caesars
#20Tennessee 8-3 27% -2 -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM Wake Forest 8-3 0% +2½ -105FanDuel
Duke 6-5 100% -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM Penn State 5-6 0% -11½ -105FanDuel
Rutgers 5-6 100% +11½ -110BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM LSU 7-4 79% +10½ -122FanDuel
#8Oklahoma 9-2 21% -10 -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM Army 5-5 67% +7 -109BetRivers
UTSA 6-5 33% -6½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM Cincinnati 7-4 100% +4½ -110BetMGM
TCU 6-4 0% -4 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM Troy 7-4 33% +7 -110Caesars
Southern Miss 7-4 67% -6½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM #22Missouri 7-4 0% -2 -110Bet365
Arkansas 2-9 100% +2½ -104FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM Wisconsin 4-7 100% +2 -110Bet365
Minnesota 6-5 0% -1½ -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM #7Oregon 10-1 26% -6½ -115Bet365
Washington 8-3 74% +7 -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:30 PM Kennesaw State 8-3 50% -2 -110Bet365
Liberty 4-7 50% +2½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/293:45 PM James Madison 10-1 0% -21½ -112BetRivers
Coastal Carolina 6-5 100% +22½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/294:30 PM Florida State 5-6 100% +2½ -110BetRivers
Florida 3-8 0% -2 -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/296:30 PM Oregon State 2-9 67% +14 -114BetRivers
Washington State 5-6 33% -13½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:00 PM Rice 5-6 100% +27½ -112FanDuel
South Florida 8-3 0% -25½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:00 PM Maryland 4-7 50% +4½ -110BetMGM
Michigan State 3-8 50% -3½ -110BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:00 PM Virginia Tech 3-8 67% +11½ -115FanDuel
#19Virginia 9-2 33% -10½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:30 PM North Carolina 4-7 67% +7½ -113BetRivers
North Carolina State 6-5 33% -7 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:30 PM #10Alabama 9-2 0% -4½ -114BetRivers
Auburn 5-6 100% +5½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:30 PM Charlotte 1-10 - +30 -110Caesars
#24Tulane 9-2 - -29 -109BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:30 PM Northwestern 6-5 100% +7 -110BetMGM
#21Illinois 7-4 0% -6½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/297:30 PM UCLA 3-8 0% +20½ -105BetMGM
#15USC 8-2 100% -20½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/298:00 PM SMU 8-3 0% -10½ -108BetRivers
California 6-5 100% +12½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/299:00 PM UNLV 9-2 0% -8½ -108Caesars
Nevada 3-8 100% +8½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2910:30 PM Fresno State 7-4 0% -2½ -110Caesars
San Jose State 3-8 100% +2½ -108FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2910:30 PM #9Notre Dame 9-2 0% -32½ -110Bet365
Stanford 4-7 100% +32½ -108Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2911:00 PM Wyoming 4-7 100% +10½ -110BetMGM
Hawaii 7-4 0% -10 -110Bet365

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Louisville Cardinals vs Kentucky Wildcats Betting Trends

ATS Records

Kentucky

Louisville

TEAM MATCHUP

Kentucky

Louisville

Recent Results

Kentucky

Louisville

HEAD TO HEAD

Kentucky

Louisville

Kentucky

UPCOMING SCHEDULE

Louisville