Betting Trends: Gamecocks vs Tigers Showdown

As we gear up for the September 20, 2025, clash between the South Carolina Gamecocks and the Missouri Tigers, all eyes are on the dynamic showdown set to unfold at Memorial Stadium/Faurot Field in Columbia, MO. With the game airing on ESPN, fans can expect an exhilarating encounter as the Gamecocks look to overcome a challenging Missouri side. The betting trends favor Missouri, who have shown remarkable consistency at home, as noted in our NCAAF standings page. Their pass offense, led by a tenacious quarterback, has been a force to reckon with, averaging over 284 passing yards per game. On the other hand, South Carolina's defense has struggled to contain high-powered offenses, allowing an average of 309 total yards per game. This disparity could significantly influence the game, especially with Missouri's home advantage. The odds spread currently favors Missouri by 10 points, with a total points line set at 48.5, reflecting the expected high-scoring nature of the game. Bettors might find value in these odds, particularly given Missouri's robust record against the spread. Key players to watch include Missouri's starting quarterback, who has been instrumental in their offensive success, and South Carolina's defensive line, which needs to step up to contain Missouri's aggressive pass attack. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.