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As we gear up for the October 11, 2025 showdown between the Northwestern Wildcats and the Penn State Nittany Lions, all eyes are on Beaver Stadium in University Park, PA. This highly anticipated Saturday football game, broadcast on Fox Sports 1, promises to be a thrilling NCAAF matchup. Both teams boast impressive stats, but it's the betting trends that are capturing attention. Northwestern's pass offense, averaging 185 yards per game, will face a formidable Penn State pass defense, allowing only 156.8 yards on average. Meanwhile, Penn State's run game, with 175.4 yards per game, will challenge Northwestern's defensive line. The key to this game could be the performance of the starting quarterbacks. Northwestern's quarterback, known for his agility, will need to outmaneuver Penn State's strong pass rush, while Penn State's QB aims to exploit Northwestern's secondary weaknesses. With Penn State's record of 3-2 straight up and 0-5 against the spread, and Northwestern's 3-2 ATS record, bettors have plenty to consider. The odds spread and total points will play a crucial role in betting decisions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on September 30, 2023, Penn State dominated with a 41-13 victory over Northwestern. With both teams having faced tough opponents recently, this game is set to be a clash of titans. Northwestern will aim to leverage their recent 7-42 win against Louisiana-Monroe, while Penn State seeks redemption after a close 37-42 loss to UCLA. Check out more NCAAF insights on our NCAAF standings page.
 Middle Tennessee 1-4- +2½ -105FanDuel | |||||||
 UTEP 1-4- +2½ -108FanDuel | |||||||
 Kennesaw State 3-2- +5½ -104FanDuel | |||||||
 Tulane 4-1- -7½ -102FanDuel | |||||||
 Georgia Southern 2-3- -1½ -105FanDuel | |||||||
 Sam Houston State 0-5- +10 -109BetRivers | |||||||
 North Texas 5-0- +1½ -115FanDuel | |||||||
 Colorado State 1-4- +5½ -110FanDuel | |||||||
 Washington 4-1- -9½ -115FanDuel | |||||||
 Cincinnati 4-1- -9½ -110FanDuel | |||||||
 Army 2-3- -14½ -110FanDuel | |||||||
 #18Florida State 3-2- -9½ -110FanDuel | |||||||
 Michigan State 3-2- -4½ -115FanDuel | |||||||
 #19Missouri 5-0- +5½ -110FanDuel | |||||||
 #22Illinois 5-1- +15½ -105FanDuel | |||||||
 SMU 3-2- -20½ -115FanDuel | |||||||
 Oklahoma State 1-4- +9½ -115FanDuel | |||||||
 Akron 2-4- - | |||||||
 James Madison 4-1- - | |||||||
 Bowling Green 2-3- - | |||||||
 #4Ole Miss 5-0- -33½ -115FanDuel | |||||||
 Eastern Michigan 1-5- - | |||||||
 Kent State 1-4- - | |||||||
 #7Penn State 3-2- -20½ -110FanDuel | |||||||
 #17Georgia Tech 5-0- -15½ -105FanDuel | |||||||
 Colorado 2-4- +4½ -110FanDuel | |||||||
 Maryland 4-1- +6½ -108FanDuel | |||||||
 Kansas State 2-4- +1½ -118FanDuel | |||||||
 #21Notre Dame 3-2- -22½ -110FanDuel | |||||||
 #2Oregon 5-0- -9½ -115FanDuel | |||||||
 Oregon State 0-6- +6½ -115FanDuel | |||||||
 #9Texas 3-2- -3½ -112FanDuel | |||||||
 UNLV 5-0- -5½ -115FanDuel | |||||||
 Western Michigan 3-3- - | |||||||
 Marshall 2-3- - | |||||||
 Georgia State 1-4- - | |||||||
 Temple 3-2- - | |||||||
 #15Tennessee 4-1- -12½ -112BetRivers | |||||||
 Florida Atlantic 2-3- - | |||||||
 Wisconsin 2-3- +3½ -122FanDuel | |||||||
 #6Texas A&M 5-0- -7½ -115FanDuel | |||||||
 Wyoming 2-3- -1½ +100FanDuel | |||||||
 Coastal Carolina 2-3- - | |||||||
 Boston College 1-4- +14½ -122FanDuel | |||||||
 #11Texas Tech 5-0- -11½ -110FanDuel | |||||||
 USC 4-1- +1½ -110BetMGM | |||||||
 Minnesota 3-2- -9½ -115FanDuel | |||||||
 Auburn 3-2- +6½ -110BetMGM | |||||||
 UTSA 2-3- - | |||||||
 #13LSU 4-1- -10½ -110FanDuel | |||||||
 Arizona 4-1- +1½ -105FanDuel | |||||||
 Texas State 3-2- - | |||||||
 Boise State 3-2- -16½ -110FanDuel | |||||||
 Utah 4-1- -4½ -112FanDuel | |||||||
 Nevada 1-4- +5½ -110FanDuel | |||||||
 Hawaii 4-2- -2½ -105FanDuel |
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