Nov 22, 2025 3:30 PM EST

Week 13

#15 USC

9-1

#7 Oregon

ORE

-10 (-110)o59½ (-110)

CBS

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USC Trojans vs Oregon Ducks Odds

Updated:Nov 21, 2025 1:53 AM EST

The upcoming clash on November 22, 2025, between the USC Trojans and Oregon Ducks at Autzen Stadium in Eugene, OR, promises thrilling Saturday football action in the 2025-26 NCAAF season. This matchup, broadcast on CBS, is a must-watch for college football fans and bettors alike.

Current odds favor the Oregon Ducks as the favorite with a point spread of -1½ -108, down from the opening -1½ -118, indicating a slight shift in betting lines towards the Ducks. Meanwhile, the USC Trojans are the underdogs at +1½ -112, giving bettors a competitive edge depending on their pick. Totals are set at 59½ with the under at -112 favored over the over at -108, suggesting a potentially defensive game.

Understanding these odds and betting lines is crucial for making informed wagers. The movement in the point spread from its opening line reflects changing perceptions of team strengths, which can significantly impact betting strategies. Bettors can leverage this data to find value bets and maximize their potential returns.

For those ready to dive deeper, the NCAAF odds page offers comprehensive insights and updates. Additionally, starting an OddsTrader Turbo subscription can help bettors gain an edge with real-time odds analysis. Place your bets with a trusted U.S. regulated sportsbook like Caesars to ensure a safe and profitable betting experience.

What are the current odds for the USC Trojans vs Oregon Ducks game?

NCAAF

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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NCAAF Fri 11/21

Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/218:00 PM Florida State 5-5 56% -5½ -110BetMGM
North Carolina State 5-5 44% +6 -108Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/2110:30 PM Hawaii 7-3 59% +3 -110Bet365
UNLV 8-2 41% -2 -129SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Rutgers 5-5 70% +32½ -110BetRivers
#1Ohio State 10-0 30% -31½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Tulsa 3-7 64% +10 -105BetMGM
Army 5-4 36% -9½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Delaware 5-5 70% +17½ -108FanDuel
Wake Forest 7-3 30% -17½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM #13Miami (FL) 8-2 38% -17½ -110Bet365
Virginia Tech 3-7 62% +18½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM #22Missouri 7-3 66% +7 -110BetMGM
#8Oklahoma 8-2 34% -6½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Louisville 7-3 76% +3 -113Caesars
SMU 7-3 24% -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Kansas 5-5 65% +3½ -105BetMGM
Iowa State 6-4 35% -3½ -108Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Minnesota 6-4 61% +4 -118BetRivers
Northwestern 5-5 39% -3½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Samford 1-10 - +55½ -110FanDuel
#3Texas A&M 10-0 - -54½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:45 PM Charlotte 1-9 52% +44 -114BetRivers
#4Georgia 9-1 48% -43½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/221:00 PM Old Dominion 7-3 44% -10½ -110Bet365
Georgia Southern 5-5 56% +12½ -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/221:00 PM Washington State 5-5 69% +14 -113BetRivers
James Madison 9-1 31% -13½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/221:00 PM Baylor 5-5 70% +7 -114Caesars
Arizona 7-3 30% -6½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Ball State 4-6 13% +28½ -122FanDuel
Toledo 6-4 87% -27½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Nevada 2-8 90% +7½ -120FanDuel
Wyoming 4-6 10% -6½ -112Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Missouri State 7-3 78% +6½ -110BetMGM
Kennesaw State 7-3 22% -6½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Mercer 9-1 - +27½ -110Bet365
Auburn 4-6 - -27½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Eastern Illinois 3-8 - +50½ -110FanDuel
#10Alabama 8-2 - -50½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:30 PM Marshall 5-5 36% -4½ -114BetRivers
Appalachian State 4-6 64% +5½ -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM Connecticut 8-3 12% -7 -110Caesars
Florida Atlantic 4-6 88% +7½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM New Mexico State 3-7 75% +3½ -117BetRivers
UTEP 2-8 25% -3 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM Sam Houston State 2-8 60% +6½ -104Caesars
Middle Tennessee 1-9 40% -6½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM Liberty 4-6 70% +1½ -125BetMGM
Louisiana Tech 5-5 30% +1½ -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM South Florida 7-3 28% -21½ -108FanDuel
UAB 3-7 72% +21½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Duke 5-5 18% -6½ -120FanDuel
North Carolina 4-6 82% +7 -113Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Arkansas 2-8 85% +9 -110Bet365
#17Texas 7-3 15% -8½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM #15USC 8-2 54% +10 -110Bet365
#7Oregon 9-1 46% -9½ -118SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Michigan State 3-7 71% +17 -110Caesars
Iowa 6-4 29% -16½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM East Carolina 7-3 19% -2½ -110Bet365
UTSA 5-5 81% +2½ -108Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Kentucky 5-5 89% +9½ -110Bet365
#14Vanderbilt 8-2 11% -8½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Southern Miss 7-3 46% -1½ -107Caesars
South Alabama 3-7 54% +2½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Jacksonville State 7-3 14% +½ -110SugarHouse
Florida International 5-5 86% +1½ -120Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Syracuse 3-7 33% +36 -110Caesars
#9Notre Dame 8-2 67% -35 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:45 PM #24Tulane 8-2 22% -7½ -115FanDuel
Temple 5-5 78% +9½ -112Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM Oklahoma State 1-9 77% +14 -110Bet365
UCF 4-6 23% -13 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM #18Michigan 8-2 27% -13½ -120FanDuel
Maryland 4-6 73% +14 -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM TCU 6-4 57% +2 -110Bet365
#23Houston 8-2 43% -1 -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM Kansas State 5-5 74% +17½ -110BetMGM
#12Utah 8-2 26% -17 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM Georgia State 1-9 57% +10½ -110Bet365
Troy 6-4 43% -10 -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:15 PM Coastal Carolina 6-4 70% +24 -108Caesars
South Carolina 3-7 30% -23½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:30 PM Furman 6-5 - +41½ -110FanDuel
Clemson 5-5 - -41½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/225:00 PM Louisiana-Monroe 3-7 33% +19½ -110Bet365
Texas State 4-6 67% -18 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM Pittsburgh 7-3 92% +3 -117BetRivers
#16Georgia Tech 9-1 8% -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM Nebraska 7-3 63% +9½ -104FanDuel
Penn State 4-6 37% -8 -112Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM Colorado State 2-8 100% +17½ -115BetMGM
Boise State 6-4 0% -16½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM New Mexico 7-3 8% -3½ -102FanDuel
Air Force 3-7 92% +4 -118SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM #20Tennessee 7-3 19% -3½ -118FanDuel
Florida 3-7 81% +4½ -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM California 6-4 17% -2½ -120FanDuel
Stanford 3-7 83% +3½ -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM #21Illinois 7-3 12% -8 -114BetRivers
Wisconsin 3-7 88% +8½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM North Texas 9-1 20% -17½ -115BetMGM
Rice 5-5 80% +18½ -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:45 PM Western Kentucky 8-2 69% +22 -112Caesars
LSU 6-4 31% -21½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/228:00 PM #11Brigham Young 9-1 14% -2 -110Bet365
Cincinnati 7-3 86% +2½ -105Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/228:00 PM #25Arizona State 7-3 13% -7 -110Caesars
Colorado 3-7 87% +7½ -114FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2210:30 PM Washington 7-3 15% -10½ -109Caesars
UCLA 3-7 85% +10½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2210:30 PM San Jose State 3-7 88% +12½ -110BetMGM
San Diego State 8-2 12% -12 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2210:30 PM Utah State 5-5 100% +3 -113BetRivers
Fresno State 7-3 0% -2½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTUE 11/187:00 PM Massachusetts 0-11 14 +34½ -115BetMGM
Ohio 7-4 42 -33½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTUE 11/187:00 PM Akron 5-7 19 +3 -114BetRivers
Bowling Green 3-8 16 -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTUE 11/187:00 PM Western Michigan 7-4 35 -6 -115Bet365
Northern Illinois 3-8 19 +7½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FINALWED 11/197:00 PM Miami (OH) 6-5 37 -1½ -120BetMGM
Buffalo 5-6 20 +2½ -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FINALWED 11/197:00 PM Central Michigan 7-4 28 -7½ -110Bet365
Kent State 4-7 16 +8½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 11/207:30 PM Louisiana 5-6 34 +3 -120BetRivers
Arkansas State 5-6 30 -2½ -110Bet365

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