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The upcoming clash on September 27, 2025, between the St. Francis (PA) Red Flash and Bucknell Bison at Christy Mathewson-Memorial Stadium in Lewisburg, PA, promises an exciting encounter in the 2025-26 NCAAF season. This Saturday football match-up will be broadcasted on ESPN+, offering fans a thrilling spectacle. Our prediction model has been quite successful, particularly in point spread bets, with Bucknell favored to win. The Bison have a predicted score of 36 against the Red Flash's 14, giving Bucknell a significant advantage. Our model shows a hit rate of 56.6% for Bucknell covering the -19.5 spread, making it a bet with positive EV. For more picks and predictions, visit our NCAAF picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.