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Get ready for an exciting Friday football showdown on November 28, 2025, as the Ohio Bobcats take on the Buffalo Bulls in the 2025-26 NCAAF season at UB Stadium in Buffalo, NY. This game will be broadcasted on ESPNU, offering fans a thrilling college football experience. Our latest picks and betting tips suggest a closely contested match with Ohio edging out Buffalo 26-22, backing the Bobcats on the moneyline despite Buffalo being a +7 underdog on the spread. The predicted total score is 47.3 points, favoring the over bet with a 56.2% hit rate and a 3.8% EV, making it a smart choice for bettors.
Our prediction model has been profitable in the last 10 games, especially on the American Total market with a 60.8% hit rate and solid expected value. This consistent performance helps bettors make informed decisions and capitalize on value bets. For more in-depth analysis and additional picks, check out our NCAAF picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.