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Before the Cal Poly Mustangs face off against the Stephen F. Austin Lumberjacks on September 20, 2025, fans and bettors alike are eager to see how this NCAAF matchup will unfold at Homer Bryce Stadium in Nacogdoches, TX. The Lumberjacks are coming off a strong performance against Houston Christian, where they dominated with an 84.5% predicted win rate. Stephen F. Austin is favored to win, with a predicted score of 32 against Cal Poly's 23. However, the Mustangs have shown resilience, covering a 12.5-point spread in recent games. Our prediction model highlights the Lumberjacks as the stronger team, but bettors could find value in the point spread market. Tune in to ESPN+ for the live action and check out our NCAAF picks page for more insights. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.