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On November 2, 2024, the Louisville Cardinals will face the Clemson Tigers at Memorial Stadium in Clemson, SC. In their last matchup on November 12, 2022, the Tigers triumphed with a final score of 31-16. Clemson's strong performance at home is evident from their 4-0 straight-up home record this season, as detailed on our NCAAF standings page. This game is set for 7:30 PM and will be broadcast on ESPN networks. The current point spread favors Clemson by 10.5 points, highlighting their dominance at home. The Tigers' offensive prowess is marked by a total of 490.4 yards per game, while the Cardinals average 460 yards. Defensive stats show Clemson allowing 348.6 total yards per game, whereas Louisville concedes 359.0 yards. Bettors should note the odds spread and total points, with the over/under set at 62.0 points. The starting quarterbacks, Cade Klubnik for Clemson and Jack Plummer for Louisville, are both crucial to their teams' strategies. With Louisville's ATS record of 0-3 as away underdogs, Clemson's home advantage might be decisive. This game could be a clash of offensive strategies, making it a must-watch for football fans and bettors alike.