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FINAL
Sep 12, 2025 7:30 PM EDT
COLO 20 vs HOU 36
Week 3
3-9
Colorado
20
FINAL
36
10-3
Houston
HOU
-4½ (-110)o45½ (-107)
tvESPN, 206
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Colorado Buffaloes vs Houston Cougars Picks

Updated:Sep 12, 2025 4:36 AM EDT

Get ready for an exciting Friday football matchup on September 12, 2025, as the Colorado Buffaloes face off against the Houston Cougars at TDECU Stadium in Houston, TX. This NCAAF clash promises to be a thrilling encounter with both teams eager to secure a win. The game will be broadcasted on ESPN, making it accessible for fans nationwide.

Our betting model predicts a closely contested game with the Houston Cougars having a slight edge. We forecast a final score of Houston 27, Colorado 22. Our picks suggest taking Houston on the moneyline and considering the over 44.5 total points as a good bet. Historically, our predictions have been profitable, with a solid hit rate in similar matchups, ensuring bettors have a reliable edge.

Whether you're a seasoned bettor or new to the game, our insights and NCAAF picks page can help you make informed decisions. Don't miss out on the action and place your bets with confidence. Ready to take your betting to the next level? Start your OddsTrader Turbo subscription today and gain an edge in sports betting.

What time does the Colorado vs Houston game start?
UPCOMING GAME PREDICTION
Spread
Money
Total
team
HOUSpread
CONSENSUS LINE
-4½ (-113)
PROJECTION
COLO (22) - HOU (27)
COVER PROBABILITY
54%
EXPECTED VALUE
+0.5%
BET RATING
SEASON COVER %
2/2
100%
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