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FINAL
Oct 11, 2025 3:30 PM EDT
ISU 17 vs COLO 24
Week 7
ISU
-3 (-110)o51½ (-110)
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Iowa State Cyclones vs Colorado Buffaloes Picks
Updated:Oct 11, 2025 2:45 AM EDT
The upcoming NCAAF clash on October 11, 2025, between the Iowa State Cyclones and Colorado Buffaloes at Folsom Field in Boulder, CO, promises a thrilling showdown. The Cyclones, with a predicted score of 28, are slightly favored against the Buffaloes, who are expected to score 25. Broadcast on ESPN, this game is a part of the exciting Saturday football lineup, drawing significant attention from bettors.
Our picks suggest leaning towards Iowa State, given their 59.1% win probability and a slight edge in the spread at -2.5. Historically, the Cyclones have shown a strong performance, winning 6 of their last 10 games, making them a reliable choice for bettors. Meanwhile, Colorado, despite their home advantage, faces an uphill battle with a 40.9% win probability.
For those looking to make smart bets, consider the point spread market, where Iowa State's -2.5 spread offers a balanced EV. Our previous predictions have been profitable in this market, maintaining a solid hit rate. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
For more predictions and insights, visit our NCAAF picks page. Whether you're eyeing the moneyline or exploring parlays, this game offers numerous opportunities for an exciting wager.
UPCOMING GAME PREDICTION
Spread
Money
ISUSpread
CONSENSUS LINE
-3 (-110)
PROJECTION
ISU (28) - COLO (25)
COVER PROBABILITY
EXPECTED VALUE
-5.0%
BET RATING
SEASON COVER %
3/6
50%
NCAAF
Spread
Game
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Top 25
Top 25
Div. II & III
NCAAFEast-West shrine game
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