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The Dartmouth Big Green are set to face off against the Penn Quakers on October 4, 2025, at Franklin Field in Philadelphia, PA. This NCAAF clash is a part of the REG Week 6, promising an exciting Saturday football showdown broadcasted on ESPN+. Both teams have had fluctuating performances, but Dartmouth's recent form gives them an edge. Last year, Dartmouth secured a narrow victory against Penn with a 20-17 scoreline. The Big Green's offense, led by a solid passing game, will be a key factor. Their quarterback is likely to exploit the Quakers' defensive vulnerabilities, particularly in the passing department. Dartmouth's pass offense averages 325.5 yards per game, which could be pivotal against Penn's defense that allows 202.5 passing yards per game. Conversely, Penn's rushing attack could pose a challenge for Dartmouth's defensive line, which has shown resilience but also susceptibility at times. The betting trends favor Dartmouth, especially with their 2-0 ATS record this season, while Penn struggles at 0-2. The spread for this game is currently set at Dartmouth -3.5, with a total points line of 45.5. Considering the teams' offensive capabilities and defensive lapses, the over could be a prudent choice for bettors. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. In their last matchup on October 5, 2024, Dartmouth edged out Penn with a score of 20-17. Check out the NCAAF standings page for more insights on team performance.