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The upcoming Saturday football game on November 22, 2025, between the Harvard Crimson and Yale Bulldogs in the NCAAF league promises an exciting showdown at Yale Bowl in New Haven, CT. This game will be broadcasted on ESPNU, providing fans and bettors a great opportunity to watch and wager on this classic rivalry.
Our picks favor the Harvard Crimson with a predicted score of 28-23 over the Yale Bulldogs, expecting Harvard to cover a -7.5 point spread. The total points are predicted to hover around 50.9, making the under 50.5 a viable betting tip given the close coverage percentages on both sides. Our prediction model has been profitable in the last 10 games, winning 6 of them, especially in the 2way market with a high EV and a 63.5% hit rate, which indicates a strong confidence in the Harvard victory.
For bettors looking for smart betting decisions, these stats and predictions provide an edge to maximize potential returns. Check out our NCAAF picks for more insights and ready yourself to place your bets confidently. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.