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FINAL
Nov 22, 2025 1:00 PM EST
SIU 37 vs ILST 7
Week 13
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Southern Illinois Salukis vs Illinois State Redbirds Betting Trends
Updated:Nov 22, 2025 1:42 AM EST
The Southern Illinois Salukis are set to face the Illinois State Redbirds at Hancock Stadium in Normal, IL, on November 22, 2025, in what promises to be an intense Saturday football clash in the NCAAF league. This game provides fascinating betting trends to consider, especially given the strong offensive and defensive stats both teams bring to the table.
Illinois State boasts a robust offense averaging 388.8 total yards per game with a balanced attack of 216.4 passing yards and 172.5 rushing yards, while their defense allows around 384 total yards, showing solid resistance. Southern Illinois counters with an offense averaging 446 total yards, led by 246.8 passing yards and 199.2 rushing yards, but their defense allows slightly more at 411.3 yards per game. Both teams have shown solid performances recently, with Illinois State winning four of their last five games and Southern Illinois experiencing a mixed set of results.
The starting quarterbacks for this matchup are crucial to watch. Illinois State's quarterback, likely their starter given no injury concerns, will face a tough Southern Illinois pass rush, which averages 2.8 sacks per game. Meanwhile, Southern Illinois will rely on their quarterback to navigate Illinois State's stout pass defense, which only allows 254 passing yards per game. The battle between pass offense and pass defense will be pivotal, as will the run game, where Southern Illinois' rushing attack slightly outpaces Illinois State's run defense.
The betting odds show a spread that reflects this competitive matchup, with the total points line suggesting a moderately high-scoring game. Illinois State's ATS record at home is 2-3, while Southern Illinois is 3-3 ATS on the road, indicating bettors should look closely at these trends. The game will be broadcast on ESPN+, making it accessible for fans and bettors alike.
In their last matchup on October 5, 2024, Illinois State dominated Southern Illinois 45-10, a result that could influence betting insights for this game. The Redbirds have a strong home record, detailed on our NCAAF standings page, which could play a significant role in this Saturday football showdown.
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ATS Records
All
6-6 (117th)Against the Spread11-6 (37th)
7-5 (108th)Straight Up12-5 (48th)
-2.1Straight Up Units+14.9
5-7Over / Under10-7
TEAM MATCHUP
OFF
DEF
OFF
DEF
36.4Points30.8
446.8Total Yards390.4
6.9Yards Per Play5.7
239.5Passing Yards220.5
18.8 - 30.7 (61.1%)Completions-Attempts20.5 - 32 (64.2%)
7.8Yards Per Passing Play6.9
2.6Sacks-Yards Lost2.8
207.3Rushing Yards169.9
34.8Attempts37.4
6Yards Per Rush4.5
22.21st Downs23
10.2Passing10.1
11Rushing8.2
1Penalties1.5
6.3 / 12.3 (50.7%)3rd Down5.7 / 13.1 (43.5%)
0.9 / 1.5 (61.1%)4th Down1.2 / 1.9 (65.6%)
4.1 / 4.3 (94.2%)Red Zone3.3 / 3.9 (84.8%)
5.4 (40.8)Penalties (Yards)4.2 (39.2)
0.4Interceptions0.8
0.7Fumbles Lost0.4
66.6Total Plays72.5
6.3Kickoffs5.6
1.8Returns1.8
29.4Yards43.8
16.8Yards Per Return24
3Punts3.6
0.8Returns1.3
14.2Yards5.9
17Yards Per Return4.6
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 TCU - -6½ -110Bovada | |||||||
 Valparaiso - - | |||||||
 USC - -35½ -108Heritage | |||||||
 Virginia - -3 -110MyBookie | |||||||
 North Dakota State - -8½ -105BetOnline | |||||||
 Eastern Michigan - -7½ -110Bovada | |||||||
 Florida State - -30½ -108Heritage | |||||||
 Stanford - -3½ -108Heritage | |||||||
 UNLV - -3 -115Bookmaker | |||||||
 Rutgers - -30½ -108Heritage | |||||||
 Wake Forest - -22½ -108Heritage | |||||||
 Kennesaw State - - | |||||||
 Buffalo - - | |||||||
 Delaware - - | |||||||
 UCF - - | |||||||
 Georgia Tech - -7 -110BetOnline | |||||||
 Minnesota - - | |||||||
 Missouri - - | |||||||
 Illinois - -27½ -108Heritage | |||||||
 Utah - - | |||||||
Eastern Michigan - -3½ -108Heritage | |||||||
 Georgia State - - | |||||||
 Purdue - - | |||||||
 Michigan State - -10½ -105BetOnline | |||||||
 Kansas - - | |||||||
USC - -22½ -110BetOnline | |||||||
Stanford - +23 -105BetOnline | |||||||
 West Virginia - -17½ -105BetOnline | |||||||
 James Madison - -6 -110BetOnline | |||||||
 Indiana - -39½ -108Heritage | |||||||
 Alabama - -26½ -108Heritage | |||||||
 Nebraska - -23½ -105BetOnline | |||||||
 Houston - -18½ -108Heritage | |||||||
 Connecticut - - | |||||||
 Syracuse - - | |||||||
 Bowling Green - - | |||||||
 Army - - | |||||||
 Pittsburgh - -15½ -110Bovada | |||||||
 Ohio State - -49½ -110BetOnline | |||||||
 South Carolina - -34½ -108Heritage | |||||||
 Oklahoma - -40½ -105BetOnline | |||||||
 Iowa State - - | |||||||
 Kentucky - - | |||||||
 Air Force - - | |||||||
 Temple - - | |||||||
 Georgia - - | |||||||
 Cincinnati - -7½ -108Heritage | |||||||
 Penn State - -22½ -110BetOnline | |||||||
 Duke - -8 -110Bookmaker | |||||||
 Texas - -30½ -110BetOnline | |||||||
 Oregon - -24½ -108Heritage | |||||||
 Auburn - -7 -105Bookmaker | |||||||
 Tennessee - - | |||||||
 Appalachian State - - | |||||||
 Charlotte - - | |||||||
 UTSA - - | |||||||
North Dakota State - - | |||||||
 Navy - - | |||||||
 Tulsa - +12½ -108Heritage | |||||||
 Iowa - -30 -110Bookmaker | |||||||
 Arkansas - - | |||||||
 Southern Miss - - | |||||||
 Colorado State - -3½ -108Heritage | |||||||
 Old Dominion - - | |||||||
 South Florida - -12 -108Heritage | |||||||
 Texas A&M - -38½ -110BetOnline | |||||||
 Troy - -17 -112Bookmaker | |||||||
 Memphis - -10½ -108Heritage | |||||||
 South Alabama - - | |||||||
 Middle Tennessee - - | |||||||
 Kansas State - - | |||||||
 Utah State - - | |||||||
 Jacksonville State - - | |||||||
 Vanderbilt - - | |||||||
 Georgia Southern - - | |||||||
 Texas Tech - - | |||||||
 Rice - - | |||||||
 Michigan - -26½ -108Heritage | |||||||
 Mississippi State - -28 -110Bookmaker | |||||||
 LSU - -11 -110MyBookie | |||||||
 Virginia Tech - - | |||||||
 Louisiana Tech - - | |||||||
 Florida - -26 -110BetOnline | |||||||
 Northwestern - - | |||||||
 Louisiana - - | |||||||
 Maryland - - | |||||||
 Brigham Young - - | |||||||
 New Mexico State - - | |||||||
 Arizona - - | |||||||
 San Diego State - - | |||||||
 New Mexico - -12 -108Heritage | |||||||
 Hawaii - +2½ -110MyBookie | |||||||
 Arizona State - - | |||||||
 Sacramento State - - | |||||||
 California - PK -110BetOnline | |||||||
 Nevada - +3½ -115BetOnline | |||||||
 Washington - -21½ -108Heritage | |||||||
 Notre Dame - -20½ -108Heritage | |||||||
 Ole Miss - -4½ -110BetOnline | |||||||
Florida State - +3 -115BetOnline |
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