- Spread
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
FINAL
Oct 4, 2025 7:00 PM EDT
INST 27 vs SIU 55
Week 6
SIU
-23½ (-115)o58½ (-115)
ESPN+BETCAST
PLAYS
MATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
WEATHER
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
Southern Illinois Salukis vs Indiana State Picks
Updated:Oct 4, 2025 6:23 AM EDT
The Indiana State Sycamores are set to clash with the Southern Illinois Salukis on October 4, 2025, in a thrilling NCAAF showdown at Saluki Stadium in Carbondale, IL. This Saturday football game promises to deliver excitement as both teams aim to secure a crucial win in Week 6 of the season. The Sycamores, coming off a challenging game against the Montana Grizzlies, are eager to bounce back, while the Salukis look to capitalize on their home advantage.
Our prediction model gives the Southern Illinois Salukis a slight edge in this matchup. With a predicted score of 24-21, we anticipate a close contest. The Salukis have shown resilience, especially in home games, and our chosen pick is the Salukis covering the spread. Our model's hit rate for similar matchups stands at a solid 62%, making this a promising bet.
Catch all the action live on ESPN+ and don't miss your chance to place smart bets with the latest NCAAF picks. Ready to elevate your betting strategy? Explore OddsTrader Turbo for insights that can give you an edge. Southern Illinois' ability to cover the spread has been profitable in recent games, boasting a strong EV. With Saturday football excitement in the air, this is a game that bettors won't want to miss.
UPCOMING GAME PREDICTION
Spread
Money
Total
INSTSpread
CONSENSUS LINE
+23½ (-110)
PROJECTION
INST (19) - SIU (40)
COVER PROBABILITY
EXPECTED VALUE
+6.1%
BET RATING
SEASON COVER %
2/4
50%
NCAAF
Spread
Game
- Game
- 1H
- 2H
- 1Q
- 2Q
- 3Q
- 4Q
Top 25
Top 25
Div. II & III
NCAAFEast-West shrine game
Download the app© OddsTrader 2026 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader no longer operates under any U.S. license, including Pennsylvania.
Seek help with a gambling addiction at 1-800-Gambler.