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FINAL
Sep 27, 2025 7:00 PM EDT
JVST 25 vs USM 42
Week 5
9-5
Jacksonville State
25
FINAL
42
7-6
Southern Miss
USM
-4½ (-110)o56 (-110)
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Jacksonville State vs Southern Miss Picks

Updated:Sep 27, 2025 6:57 AM EDT

Get ready for some thrilling Saturday football as the Jacksonville State Gamecocks face off against the Southern Miss Golden Eagles on September 27, 2025. This NCAAF matchup promises to be a nail-biter at M.M. Roberts Stadium in Hattiesburg, MS. Catch all the action live on ESPN+ and make your picks wisely. Our prediction model gives Southern Miss a 66.1% chance to win, with a predicted score of 31-26 in their favor. Jacksonville State, however, is not to be underestimated, as they come in with a point spread of +4, showcasing their potential to cover. Our predictions have a solid hit rate, especially in the American Total market, which has been profitable in recent games. With a predicted total score of 57.03, the Over 54.5 seems like a smart bet. Dive into our NCAAF picks for more insights and get an edge in your betting strategy. Explore our NCAAF picks.

Our past predictions have shown great accuracy, especially in point spreads. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

What is the best bet for the Jacksonville State vs Southern Miss game?
UPCOMING GAME PREDICTION
Spread
Money
Total
team
USMSpread
CONSENSUS LINE
-4 (-112)
PROJECTION
JVST (26) - USM (31)
COVER PROBABILITY
53%
EXPECTED VALUE
-1.8%
BET RATING
SEASON COVER %
2/4
50%
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