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FINAL
Nov 22, 2025 7:45 PM EST
WKU 10 vs LSU 13
Week 13
9-4
Western Kentucky
10
FINAL
13
7-6
LSU
LSU
-24½ (-108)o52 (-110)
tvSEC Network, ESPN Networks, 611
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Western Kentucky Hilltoppers vs LSU Tigers Odds

Updated:Nov 22, 2025 2:29 AM EST

The upcoming NCAAF clash on November 22, 2025, between the Western Kentucky Hilltoppers and LSU Tigers at Tiger Stadium in Baton Rouge, LA, promises an exciting Saturday football showdown. Fans can catch all the action live on SEC Network and ESPN Networks, making it a must-watch event.

Current odds favor the home team, LSU Tigers, as the favorites with a point spread of -22 -109 at Caesars sportsbook, compared to the Western Kentucky Hilltoppers at +22 -110. The opening odds showed a similar spread but with slightly different pricing, indicating steady confidence in LSU maintaining their edge. Bettors should note the total points over/under is set at 50.5, with the over at -113 and the under at -108, providing a balanced market for total points scored.

Understanding these odds and betting lines is crucial for making informed wagers. The significant point spread suggests LSU is expected to dominate, but Western Kentucky could provide value as the underdog. By analyzing the odds movement and current betting trends, bettors can identify smart opportunities to place their bets.

For a deeper dive into NCAAF odds and more betting insights, visit our NCAAF odds page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

When is the Western Kentucky Hilltoppers vs LSU Tigers game?
Spread (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
Western KentuckySpread
+5.4%
EV
+5.4%
56%
team
LSUSpread
-8.3%
EV
-8.3%
44%
MONEYLINE (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
Western KentuckyMONEYLINE
+0.9%
EV
+0.9%
7%
team
LSUMONEYLINE
-4.0%
EV
-4.0%
93%
Total (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
over
OVERTotal
-2.1%
EV
-2.1%
51%
under
UNDERTotal
-1.8%
EV
-1.8%
50%
Spread (1H)
BEST LINE
team
Western KentuckySpread
team
LSUSpread
MONEYLINE (1H)
BEST LINE
team
Western KentuckyMONEYLINE
team
LSUMONEYLINE
Total (1H)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (2H)
BEST LINE
team
Western KentuckySpread
team
LSUSpread
MONEYLINE (2H)
BEST LINE
team
Western KentuckyMONEYLINE
team
LSUMONEYLINE
Total (2H)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (1Q)
BEST LINE
team
Western KentuckySpread
team
LSUSpread
MONEYLINE (1Q)
BEST LINE
team
Western KentuckyMONEYLINE
team
LSUMONEYLINE
Total (1Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
The best odds available today for Western Kentucky is +25 -108 at Heritage and for LSU -24 -110 at MyBookie. The total for the over/under line is o51½ -110 at MyBookie.
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