Betting Trends: Michigan State Spartans vs Nebraska Cornhuskers

On October 4, 2025, the Nebraska Cornhuskers will host the Michigan State Spartans at Memorial Stadium in Lincoln, NE. This Week 6 NCAAF matchup is set for 4 PM, with coverage on Fox Sports 1. The Cornhuskers, playing at home, are favored by 12.5 points with a total points line set at 48.5. The Cornhuskers' potent passing offense, averaging 351.75 yards per game, will face a challenge from the Spartans' defense, which allows an average of 263.5 passing yards. Nebraska's quarterback is expected to exploit Michigan State's defense, which has struggled against the pass in recent games. The Spartans, on the other hand, will rely on their rushing game, with an average of 154 rushing yards, to counter Nebraska's defense that allows 173.5 rushing yards per game. In their last encounter on November 4, 2023, the Spartans edged out the Cornhuskers 20-17. For bettors, the Cornhuskers' strong ATS record at home (2-1) could be enticing. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.