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FINAL
Sep 20, 2025 3:30 PM EDT
PUR 30 vs ND 56
Week 4
2-10
Purdue
30
FINAL
56
10-2
#22 Notre Dame
ND
-24½ (-110)o51½ (-110)
tvNBC
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Purdue Boilermakers vs Notre Dame Betting Trends

Updated:Sep 20, 2025 3:48 AM EDT

The Notre Dame Fighting Irish are set to face the Purdue Boilermakers in a thrilling NCAAF showdown on September 20, 2025, at Notre Dame Stadium in South Bend, IN. The Fighting Irish, led by their dynamic quarterback, aim to bounce back after a narrow loss to Texas A&M. With a potent pass offense averaging 257 yards per game, Notre Dame is poised to exploit Purdue's defense, which has struggled against the pass this season. On the other hand, Purdue's run game, led by their aggressive offensive line, could pose a challenge to Notre Dame's defense, which has allowed an average of 123.5 rushing yards per game.

The odds favor Notre Dame with a point spread of -25.5, while Purdue is looking to upset with a spread of +25.5. The total points over/under is set at 51.5. Both teams have had mixed results against the spread, as seen on our NCAAF standings page. In their last encounter on September 14, 2024, Notre Dame dominated Purdue with a 66-7 victory, showcasing their offensive prowess.

For sports bettors, this game offers intriguing betting trends. Notre Dame's strong home record and Purdue's recent struggles on the road make the Fighting Irish a promising pick. Start your OddsTrader Turbo subscription for more in-depth game insights and betting stats.

Where is the Notre Dame vs Purdue game being played?

ATS Records

Purdue

Notre Dame

All
  • All
  • 1st half
  • 2nd half
  • 1st quarter
  • 2nd quarter
  • 3rd quarter
  • 4th quarter
4-7-1 (224th)Against the Spread6-6 (118th)
2-10 (248th)Straight Up10-2 (22nd)
-9.8Straight Up Units-0.9
4-8Over / Under7-5

TEAM MATCHUP

Purdue

Notre Dame

OFF
DEF
OFF
DEF
18.8Points42
342.8Total Yards458.5
5.2Yards Per Play7.6
217.2Passing Yards255.1
19.8 - 33.8 (58.8%)Completions-Attempts18.1 - 26.9 (67.2%)
6.4Yards Per Passing Play9.5
10.2Sacks-Yards Lost8.4
125.6Rushing Yards203.4
31.3Attempts35.8
4Yards Per Rush5.7
19.31st Downs22.7
10.7Passing11.4
6.9Rushing9.1
1.7Penalties2.2
5.1 / 13.3 (38.4%)3rd Down5.4 / 11.3 (48.1%)
1.3 / 2.1 (60%)4th Down1.4 / 2.6 (54.8%)
2.3 / 3.1 (75.7%)Red Zone3.5 / 4.6 (76.4%)
4.8 (46.8)Penalties (Yards)5.5 (53.1)
1.1Interceptions0.5
0.7Fumbles Lost0.3
66.8Total Plays63.7
4.4Kickoffs7.2
2.4Returns1.8
52.3Yards44.3
21.6Yards Per Return25.3
4.2Punts2.1
0.7Returns1.6
2.2Yards17.7
3.3Yards Per Return11.2

Recent Results

Purdue

Notre Dame

Game
Score
ATS
O/U
vs USC
Sep 13, 2025
L
17-33
W
+20½
U
59½
vs Southern Illinois
Sep 6, 2025
W
34-17
L
-20½
U
52½
vs Ball State
Aug 30, 2025
W
31-0
W
-16½
U
48½
at Indiana
Nov 30, 2024
L
0-66
L
+29½
O
56½
at Michigan State
Nov 22, 2024
L
17-24
W
+14
U
49
vs Penn State
Nov 16, 2024
L
10-49
L
+29½
O
51½
at Ohio State
Nov 9, 2024
L
0-45
L
+37½
U
54½
vs Northwestern
Nov 2, 2024
L
20-26
L
-2½
O
44½
vs Oregon
Oct 18, 2024
L
0-35
L
+30½
U
61
at Illinois
Oct 12, 2024
L
49-50
W
+22½
O
47½
Game
Score
ATS
O/U
vs Texas A&M
Sep 13, 2025
L
40-41
L
-6½
O
49½
at Miami (FL)
Aug 31, 2025
L
24-27
L
-3
O
50½
vs Ohio State
Jan 20, 2025
L
23-34
L
+8½
O
45½
at Penn State
Jan 9, 2025
W
27-24
W
+1
O
45
at Georgia
Jan 2, 2025
W
23-10
W
-1
U
45½
vs Indiana
Dec 20, 2024
W
27-17
W
-7
U
50½
at USC
Nov 30, 2024
W
49-35
W
-7
O
52½
vs Army
Nov 23, 2024
W
49-14
W
-14½
O
44½
vs Virginia
Nov 16, 2024
W
35-14
W
-20½
U
51
vs Florida State
Nov 9, 2024
W
52-3
W
-25½
O
43½
View Full Season Game Log

HEAD TO HEAD

Purdue

PUR

Notre Dame

ND
Matchup
SU
ATS
O/U
Notre Dame @ PurdueSep 14, 2024
66-7
ND
-7
ND
47
O
Purdue @ Notre DameSep 18, 2021
13-27
ND
-7½
ND
58½
U

Purdue

UPCOMING SCHEDULE

Notre Dame

Matchup
Date
Time
vs Illinois
tvBTN, 610
Oct 4, 2025
12:00 EDT
at Minnesota
tvBTN, 610
Oct 11, 2025
19:30 EDT
at Northwestern
tvBTN, 610
Oct 18, 2025
15:00 EDT
vs Rutgers
tvBTN, 610
Oct 25, 2025
12:00 EDT
at Michigan
tvBTN, 610
Nov 1, 2025
19:00 EDT
Matchup
Date
Time
at Arkansas
tvABC
Sep 27, 2025
12:00 EDT
vs Boise State
tvNBC
Oct 4, 2025
15:30 EDT
vs North Carolina State
tvPeacock
Oct 11, 2025
15:30 EDT
vs USC
tvNBC
Oct 18, 2025
19:30 EDT
at Boston College
tvESPN, 206
Nov 1, 2025
15:30 EDT
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