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The upcoming showdown between the Notre Dame Fighting Irish and the USC Trojans promises to be a thrilling encounter at the Los Angeles Memorial Coliseum. Notre Dame, with a stellar 10-1 record and a 9-2 ATS performance, stands as a formidable opponent. Their recent matchup against USC on October 14th ended with a decisive 48-20 victory, showcasing their offensive prowess. With the game being aired on CBS at 3:30 PM EST, fans and bettors alike will be keen to see if Notre Dame can maintain their unbeaten away streak. The Trojans, although struggling with a 6-5 record, boast a perfect 6-0 ATS home record, making them a tough contender on their turf. The point spread favors Notre Dame by 7.5 points, and with a total points line set at 52.5, this game is set to be a betting spectacle. For more on their ATS records, visit our NCAAF standings page. Key players to watch include Notre Dame's quarterback, who has been instrumental in their recent victories, and USC's defensive unit that will be crucial in holding off Notre Dame's high-powered offense.