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Get ready for an exciting Saturday football matchup as the Old Dominion Monarchs face off against the Virginia Tech Hokies on September 13, 2025, at Lane Stadium in Blacksburg, VA. This NCAAF Week 3 clash promises to deliver thrilling action, with both teams eager to secure a victory. The game will be broadcast on the ACC Network, ensuring fans don't miss a moment of the action. Our picks suggest a closely contested battle, with Virginia Tech predicted to edge out Old Dominion with a final score of 28-26. The Over 51 market holds a 55.7% hit rate, making it a high EV pick for savvy bettors. In previous games, our prediction model has been profitable, with a solid track record in point spread markets. Ready to make a smart bet? Start your OddsTrader Turbo subscription or place your wagers with a U.S. regulated sportsbook. For more insights, check out our NCAAF picks page.