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Get ready for a thrilling Saturday football showdown on September 13, 2025, as the Villanova Wildcats take on the Penn State Nittany Lions at the West Shore Home Field at Beaver Stadium in University Park, PA. This matchup, featured in the NCAAF, promises to be a spectacle for fans and bettors alike. Our picks suggest that Villanova, currently a +48.5 underdog, will cover the spread, boasting a 66.1% hit rate and a promising 13.7% EV. With a predicted total score just shy of the line, our betting tips also lean towards the under 56.5. Catch all the action on Fox Sports 1 and make sure to check out our NCAAF picks page for more insights. Our prediction model has been on fire, especially in the point spread market, where we’ve hit 7 out of the last 10 predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.