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Before the big game on September 13, 2025, between the Pittsburgh Panthers and the West Virginia Mountaineers at Mountaineer Field at Milan Puskar Stadium in Morgantown, WV, anticipation is building among college football fans. The Panthers, with a predicted score of 31, are favored with a 63.5% win probability. Meanwhile, the Mountaineers, predicted to score 26, are looking to leverage their home advantage on ESPN. Our prediction model, which has been profitable in the last 10 games, suggests the best bet is on Pittsburgh. With a predicted total score of 56.5, betting on Over 56.5 could be lucrative. Explore our NCAAF picks page for more detailed insights. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook for a smart wager.