San Francisco Giants vs L.A. Dodgers Betting Trends

As the San Francisco Giants gear up to face the L.A. Dodgers on September 21, 2025, at Dodger Stadium in Los Angeles, CA, baseball fans and bettors alike are eagerly anticipating this MLB showdown. The Giants, with a record of 76-79, will be looking to upset the Dodgers, who boast a solid 88-67 record. Betting trends show the Dodgers as favorites, having won their last encounter on September 20 with a score of 7-5.

The starting pitchers for this match are Emmet Sheehan for the Dodgers, with a commendable 3.168 ERA, and Trevor McDonald for the Giants, who has yet to secure a win with a 9.0 ERA. Sheehan's ability to strike out batters at a high rate and maintain a low WHIP of 1.0561 gives the Dodgers a clear edge. McDonald, on the other hand, will need to improve his performance against right-handed hitters to keep the Giants in the game.

Looking at the odds, the Dodgers are favorites with a moneyline of -240, while the Giants are at +196. The point spread stands at -1.5 for the Dodgers. The game's total is set at 9 runs, with the over at -115 and the under at -105. These odds suggest a potentially high-scoring game, favoring the Dodgers' strong batting lineup.

For fans watching on NBCS-BA and those betting, the key will be to monitor the pitching duel and how each team's lineup performs. For comprehensive betting insights, consider a Start your OddsTrader Turbo subscription and check out the MLB standings page for detailed team records.