Pittsburgh Pirates vs San Francisco Giants: Detailed Game Insights

The upcoming MLB matchup between the Pittsburgh Pirates and the San Francisco Giants promises to be an exciting clash at Oracle Park in San Francisco, CA, on July 28, 2025, at 21:45 ET. The Giants, playing at home, have the advantage with a -130 odds on the moneyline according to Caesars, while the Pirates have a +110 underdog status. This game will be broadcasted on SportsNet PT, offering viewers a thrilling experience. In their last matchup on May 23, 2024, the Giants narrowly defeated the Pirates 7-6, a game packed with intense moments. Mitch Keller, the Pirates' starting pitcher, brings a 3.528 ERA and a right-handed throw to the mound, facing the Giants' powerful lineup. The Pirates have shown resilience, winning their last three games against Arizona, while the Giants have struggled against New York. Both teams have a history of close encounters, making this game a must-watch. Check out our MLB standings page for more detailed ATS records. The total points line is set at 8, with the UNDER being favored at -125, indicating a potentially low-scoring game.