- Run Line
- Money
- Total
- Merged
The upcoming MLB matchup between the Chicago White Sox and Arizona Diamondbacks is set for April 21, 2026, at Chase Field in Phoenix, AZ. Broadcast on chsn, the game features a run line favoring Arizona at -1.5 -110, with opening odds showing a slight shift from the initial line, indicating increased confidence in the Diamondbacks. Moneyline odds have Arizona as favorites at -145, while the White Sox are +131. Total runs are set at 9 with balanced over under betting odds.
These betting lines offer valuable insights into market expectations ahead of this regular season game. For comprehensive MLB odds, visit our MLB odds page.
TBC. Legumina (R) 44-3342% -135BetAnything | |||||||
PITB. Chandler (R) 40-4071% +135Everygame | |||||||
SFL. Roupp (R) 33-4657% -122Bookmaker | |||||||
![]() DETT. Melton (R) 34-4667% -104Bookmaker | |||||||
WSHC. Cavalli (R) 41-4070% +160Everygame | |||||||
![]() TORK. Gausman (R) 39-4118% -144Bet105 | |||||||
NYMF. Peralta (R) 34-4618% -102Bookmaker | |||||||
BOSC. Early (L) 32-4668% +145Everygame | |||||||
STLM. McGreevy (R) 42-3612% -129BetOnline |