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As the Cleveland Guardians prepare to face the Detroit Tigers at Comerica Park in Detroit, MI on September 17, 2025, MLB fans and bettors alike are gearing up for an exciting showdown. With the Guardians coming off a recent victory against the Tigers, they are looking to continue their winning streak. The game will be broadcasted on Fox Sports 1, providing fans ample opportunity to catch the action live.
Currently, the run line stands at +1.5 -170 for the Guardians and -1.5 +143 for the Tigers, according to Caesars. The moneyline odds are +122 for the Guardians and -145 for the Tigers, indicating a slight edge for Detroit as favorites in this matchup. Meanwhile, the total is set at o8 -115, suggesting a potentially high-scoring game.
For those interested in the best betting odds, it's crucial to note the current odds compared to the opening lines. The Guardians' moneyline has shifted slightly, reflecting their recent form and the Tigers' home advantage. These insights can help bettors make informed decisions, especially if they are looking to place a wager with a U.S. regulated sportsbook or start an OddsTrader Turbo subscription. Ready to bet smarter? Start your OddsTrader Turbo subscription now.
For more detailed analysis and to stay ahead of the game, check out our MLB odds page. Whether you're a seasoned bettor or new to the game, these odds and insights are designed to give you the edge you need.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1230% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1116% -106BetAnything | |||||||
TBS. Matz (L) 12-1076% +103BetOnline | |||||||
WSHF. Griffin (L) 10-1373% +136BetOnline | |||||||
BOSC. Early (L) 9-1351% -121Everygame | |||||||
NYMN. McLean (R) 7-1524% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-916% -125Bookmaker | |||||||
KCK. Bubic (L) 7-1612% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1478% +130Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1380% -108Bookmaker | |||||||
SEAL. Castillo (R) 10-1426% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-912% -142Bet105 | |||||||
SFL. Roupp (R) 9-1390% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |