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FINAL
Sep 21, 2025 7:10 PM EDT
SEA 7 vs HOU 3
SEA
-142o8½ (-105)
ESPN, SCHNBETCAST
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MATCHUP
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Seattle Mariners vs Houston Astros Odds
Updated:Sep 21, 2025 2:55 AM EDT
Get ready for an electrifying MLB clash as the Seattle Mariners take on the Houston Astros on September 21, 2025, at Daikin Park in Houston, TX. The Mariners, led by their strong lineup, are favorites with odds of -140, while the Astros are underdogs at +118. The run line is set at -1.5 +115 for Seattle and +1.5 -135 for Houston. The over/under is fixed at 8, with the over priced at -115 and the under at -105.
This matchup is set to be broadcasted on ESPN, offering a thrilling spectacle for baseball enthusiasts and bettors alike. The Mariners have shown impressive consistency, making them a preferred choice for many bettors. However, the Astros, playing on their home turf, are known for pulling off surprises, which adds an intriguing layer to this encounter.
Analyzing the betting lines, the Mariners' position as favorites reflects their recent form and strong performances. The Astros' underdog status, however, could be enticing for those looking to capitalize on potential upsets. The current odds have shifted slightly from the opening, indicating a growing confidence in the Mariners.
For those looking to place smart bets, consider the run line and the under total markets, as these offer valuable insights into potential outcomes. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Check out the latest MLB odds for more insights.
MONEYLINE (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
SeattleMONEYLINE
+3.5%
EV
+3.5%
HoustonMONEYLINE
-6.6%
EV
-6.6%
Total (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
OVERTotal
-15.7%
EV
-15.7%
UNDERTotal
+1.8%
EV
+1.8%
Run Line (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
SeattleRun Line
+0.7%
EV
+0.7%
HoustonRun Line
-2.3%
EV
-2.3%
MONEYLINE (1st 5)
BEST LINE
SeattleMONEYLINE
HoustonMONEYLINE
Total (1st 5)
BEST LINE
OVERTotal
UNDERTotal
Run Line (1st 5)
BEST LINE
SeattleRun Line
HoustonRun Line
MLB
Money
Game
- Game
- 1st 5
MLBThu 06/25
 TBC. Legumina (R) 44-3329% -136Bet105 | |||||||
 PITB. Chandler (R) 40-40100% +133Everygame | |||||||
 SFL. Roupp (R) 33-4633% -127BetAnything | |||||||
 DETT. Melton (R) 34-4617% -108BetAnything | |||||||
 WSHC. Cavalli (R) 41-4086% +167Bookmaker | |||||||
 TORK. Gausman (R) 39-410% -147BetOnline | |||||||
 NYMF. Peralta (R) 34-4625% -105Bet105 | |||||||
 BOSC. Early (L) 32-46100% +144Bookmaker | |||||||
 STLM. McGreevy (R) 42-360% -125BetOnline |
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