- Run Line
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
FINAL
Sep 21, 2025 7:10 PM EDT
SEA 7 vs HOU 3
SEA
-142o8½ (-105)
ESPN, SCHNBETCAST
PLAYS
MATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
INJURIES
WEATHER
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
Seattle Mariners Vs Houston Astros Picks
Updated:Sep 21, 2025 2:54 AM EDT
As we gear up for the showdown between the Seattle Mariners and the Houston Astros on September 21, 2025, at Daikin Park in Houston, TX, baseball enthusiasts and bettors alike are in for a treat. The Mariners have been showing a strong form recently, and with a predicted score of 4.5 against Houston's 3.3, they appear poised to secure a victory. Our model indicates a 62.7% probability of Seattle winning with a positive EV of 5.2%. Houston, however, isn't one to be underestimated, especially at home. The Astros have a 53.4% chance to cover the spread at +1.5 with a slightly negative EV. Given these insights, Seattle looks like the stronger pick. Broadcasting on ESPN, this MLB clash promises excitement. Expect a close game with a predicted total score under 8, making it a strategic pick for bettors. Our recent predictions have been quite accurate, with a strong hit rate on Seattle's wins. For more winning picks, check out our MLB picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Run Line
Money
Total
SEAMoney
CONSENSUS LINE
-150
PROJECTION
SEA (4.5) - HOU (3.3)
COVER PROBABILITY
EXPECTED VALUE
+3.5%
BET RATING
SEASON COVER %
86/155
55%
MLB
Money
Game
- Game
- 1st 5
MLBThu 06/25
 TBC. Legumina (R) 44-3329% -136Bet105 | |||||||
 PITB. Chandler (R) 40-40100% +133Everygame | |||||||
 SFL. Roupp (R) 33-4633% -127BetAnything | |||||||
 DETT. Melton (R) 34-4617% -108BetAnything | |||||||
 WSHC. Cavalli (R) 41-4086% +167Bookmaker | |||||||
 TORK. Gausman (R) 39-410% -147BetOnline | |||||||
 NYMF. Peralta (R) 34-4625% -105Bet105 | |||||||
 BOSC. Early (L) 32-46100% +144Bookmaker | |||||||
 STLM. McGreevy (R) 42-360% -125BetOnline |
Download the app© OddsTrader 2026 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader no longer operates under any U.S. license, including Pennsylvania.
Seek help with a gambling addiction at 1-800-Gambler.