Jan 26, 2026 7:00 PM EST

18-1

#5 Duke

DUKE

-7½ (-110)o157½ (-110)

ESPN

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Louisville Cardinals vs Duke Blue Devils Betting Trends

Updated:Jan 26, 2026 1:17 AM EST

The upcoming NCAAB matchup on January 26, 2026, features the Louisville Cardinals visiting the Duke Blue Devils at Cameron Indoor Stadium in Durham, NC. This game promises to deliver thrilling basketball action and valuable betting insights for fans and bettors alike. The Duke Blue Devils, boasting a strong home record of 12-1, are favored by 7.5 points with a total points line set at 157.5, as shown by the latest odds from BetOnline. Louisville, with a solid 14-5 overall record and a 4-3 away record, will look to challenge Duke’s dominance on their home court.

Analyzing the teams' stats, Duke averages 85.7 points per game and allows 69.2 points, showcasing a stout defense, while Louisville scores 87.8 points per game and concedes 71.5 points. Louisville attempts more three-pointers per game (33.84) with a slightly higher accuracy (35.3%) compared to Duke’s 26.79 attempts at 34.4%. Both teams' shooting efficiencies and defensive ratings will heavily influence the game flow and betting outcomes.

Key players expected to start for Duke include their top scorers and assist leaders, while Louisville’s starting five features their consistent offensive contributors. Although some players are listed as questionable due to minor injuries, reports suggest they are likely to play, which could impact team dynamics positively.

In their last encounter on January 6, 2026, Duke edged out Louisville 84-73 in a closely contested game at Louisville’s home, a contest you can revisit in our detailed analysis of their recent showdown. Bettors should consider Duke's strong ATS record at home and Louisville's resilience on the road, visible on our NCAAB standings page when making smart wagering decisions.

For the best odds on this game, explore options like BetOnline, where Duke is favored at -7.5 and Louisville is +7.5 with competitive pricing. Tune in to ESPN for live coverage and stay informed with up-to-date betting trends to maximize your wagering strategy for this high-stakes college basketball clash.

What are the current betting odds for the Louisville vs Duke matchup?

ATS Records

Louisville

Duke

All

All
1st half
2nd half

10-9 (141st)Against the Spread11-8 (93rd)

4-3Home / Away6-7

14-5 (56th)Straight Up18-1 (11th)

4-3Home / Away12-1

-3.0Straight Up Units+1.8

-1.6Home / Away-0.2

8-11Over / Under7-12

4-3Home / Away5-8

TEAM MATCHUP

Louisville

Duke

87.8Points85.7

29.5Field Goals Made29.2

62.8Field Goals Attempted58.6

46%Field Goal Percentage49%

123 Point Field Goals Made9.2

33.83 Point Field Goals Attempted26.8

35%3 Point Field Goal Percentage34%

16.9Free Throws Made18.1

21.9Free Throws Attempted25.3

77%Free Throw Percentage71%

39Rebounds37.4

11.4Offensive Rebounds10.8

27.6Defensive Rebounds26.6

17.8Assists17.5

11.3Turnovers11.2

7.3Steals8.5

3.3Blocks4.1

19.3Personal Fouls16.6

HEAD TO HEAD

Louisville

LOU

Duke

DUKE

NCAAB

ODDS PICKS FUTURES RANKINGS STANDINGS

Live college basketball odds are always available at OddsTrader. You can keep up with your favorite teams or consider using our stats-driven NCAAB computer picks to help you make smarter wagers. Betting action intensifies during March Madness, making it crucial to track odds and betting lines in real time. New bettors can read on to learn more about NCAAB odds.

Spread

Spread
Money
Total
Merged

Game

Game
1H
2H

Today

Yesterday

NCAAB Mon 01/26

Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/266:00 PM Delaware State 5-14 - +1½ -110BetOnline
South Carolina State 4-16 - PK -110Heritage
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/266:00 PM Le Moyne 10-10 - -2½ -105Bookmaker
Fairleigh Dickinson 7-13 - +3 -110Heritage
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM #23Louisville 14-5 25% +7½ -108Heritage
#5Duke 18-1 75% -7½ -107Bookmaker
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM Penn State 9-10 - +12½ -108Heritage
Ohio State 13-6 - -12 -110BetOnline
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM Abilene Christian 10-9 75% +4½ -105Bookmaker
Tarleton State 11-9 25% -4½ -108Heritage
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM Jackson State 5-14 - +6 -110BetOnline
Florida A&M 8-9 - -6 -104Bookmaker
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM Alcorn State 3-15 - +13 -110Bovada
Bethune-Cookman 8-11 - -12½ -110BetOnline
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM Morgan State 7-13 - +9½ -110Bovada
Norfolk State 10-12 - -9 -115BetOnline
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM Central Connecticut State 10-8 - -2½ -110Heritage
Stonehill 6-14 - +3 -110Bovada
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/267:00 PM Wagner 6-12 - +10½ -115Bookmaker
LIU 12-8 - -10 -110BetOnline
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/268:00 PM Texas Rio Grande Valley 9-11 - +3½ -110BetOnline
Texas A&M-CC 11-9 - -3½ -106Bookmaker
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/269:00 PM #1Arizona 20-0 13% -1½ -122BetOnline
#13BYU 17-2 87% +2½ -115Bovada
Personalize your notifications and get updates on the teams, players or events you care about most. TUE 01/277:00 PM #7Nebraska 20-0 - -
#3Michigan 18-1 - -
Personalize your notifications and get updates on the teams, players or events you care about most. TUE 01/277:00 PM East Texas A&M 8-12 - +8 -116Bookmaker
Lamar 10-10 - -8 -105Bookmaker
Personalize your notifications and get updates on the teams, players or events you care about most. TUE 01/278:00 PM Incarnate Word 9-11 - -1½ -110Bookmaker
Houston Christian 7-13 - +1½ -110Bookmaker

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Louisville Cardinals vs Duke Blue Devils Betting Trends

ATS Records

Louisville

Duke

TEAM MATCHUP

Louisville

Duke

Recent Results

Louisville

Duke

HEAD TO HEAD

Louisville

Duke

Louisville

UPCOMING SCHEDULE

Duke