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The NCAA basketball matchup between the Saint Louis Billikens and Michigan Wolverines is scheduled for March 21, 2026, at the KeyBank Center in Buffalo, NY. Broadcast on CBS, this game features Michigan as a strong home favorite with a -12.5 point spread and a total points line set at 161.5. Michigan averages 87.2 points per game with a 51% field goal percentage and 36.3% from three-point range, while Saint Louis posts 87.7 points per game, shooting 51.2% overall and 39.8% from beyond the arc.
Michigan's defensive rating of 97.1 and Saint Louis's 97.6 suggest a competitive defensive battle. The Wolverines have a home ATS record of 9-12, whereas the Billikens are 5-5 ATS on the road, indicating moderately balanced betting trends. Key players are expected to start, with no significant injuries reported, which should maintain both teams' offensive capabilities. These betting trends and game insights provide a data-driven foundation for evaluating the upcoming contest in the 2025-26 NCAAB season.
Live college basketball odds are always available at OddsTrader. You can keep up with your favorite teams or consider using our stats-driven NCAAB computer picks to help you make smarter wagers. Betting action intensifies during March Madness, making it crucial to track odds and betting lines in real time. New bettors can read on to learn more about NCAAB odds.
![]() #3Michigan 32-364% -12½ -106Bookmaker | |||||||
![]() #11Michigan State 26-725% -4½ -108Heritage | |||||||
![]() #1Duke 33-250% -11½ -108Heritage | |||||||
#5Houston 29-650% -10½ -108Heritage | |||||||
![]() #12Gonzaga 31-357% -6 -115Bookmaker | |||||||
#13Illinois 25-825% -11 -108Heritage | |||||||
#15Nebraska 27-667% +2 -113Bet105 | |||||||
#14Arkansas 27-80% -11½ -108Heritage | |||||||
![]() #8Purdue 28-8- -7½ -108Bookmaker | |||||||
![]() #6Iowa State 28-70% -4½ -110Everygame | |||||||
![]() #17Kansas 24-10- +3½ -108Heritage | |||||||
![]() #9Virginia 30-533% +1½ -110BetAnything | |||||||
![]() #2Arizona 33-20% -11½ -108Heritage | |||||||
![]() #7Connecticut 30-5- -4 -108Heritage | |||||||
#18Alabama 24-9100% PK -108Heritage |
NC-Wilmington 27-6100% +2½ -108Heritage | |||||||
![]() Nevada 23-12100% -7 -110BetOnline | |||||||
Wake Forest 18-16- -7½ -108Heritage | |||||||
Auburn 18-16- -13½ -108Bet105 | |||||||
![]() Tulsa 27-7- -4 -117Bookmaker | |||||||
#4Florida 27-7- -10 -110BetAnything | |||||||
![]() New Mexico 24-10- -7½ -108Heritage | |||||||
Oklahoma State 20-14- -3½ -108BetOnline | |||||||
California 22-11- -5½ -110Bookmaker |