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Nov 22, 2025 2:00 PM EST
Week 13
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Eastern Illinois Panthers vs Alabama Crimson Tide Picks
Updated:Nov 21, 2025 2:08 AM EST
The upcoming Saturday football game on November 22, 2025, features the Eastern Illinois Panthers taking on the Alabama Crimson Tide at Bryant-Denny Stadium in Tuscaloosa, AL. This NCAAF Week 13 matchup promises exciting action as Alabama looks to leverage its home advantage in front of a passionate crowd, with the game broadcast on SEC Network+ for fans nationwide.
Our picks for this game favor the Alabama Crimson Tide with a predicted score of 35-17, and we expect Alabama to cover the spread. Our prediction model has been profitable in recent games, boasting a strong hit rate of 64.1% on point spreads and an EV of 11.7% in favor of Alabama, especially in home games. This makes the point spread market a high EV and reliable choice for bettors looking to place smart bets.
Eastern Illinois Panthers vs Alabama Crimson Tide is a must-watch for bettors seeking expert predictions and betting tips. Our analysis highlights Alabama's dominant performance in their last 10 games, winning 6 of those point spread bets. This consistency should give bettors confidence in placing wagers on Alabama to continue their strong form.
For more insightful picks and detailed analysis, visit our comprehensive NCAAF picks and predictions page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
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NCAAF Week 13
NCAAF Sat 11/22
 #1Ohio State 10-031% -31 -115BetRivers | |||||||
 Army 5-423% -9½ -118FanDuel | |||||||
 Wake Forest 7-333% -17½ -110Caesars | |||||||
 Virginia Tech 3-725% +18 -109Caesars | |||||||
 #8Oklahoma 8-235% -5½ -110Bet365 | |||||||
 SMU 7-354% -3½ -117SugarHouse | |||||||
 Iowa State 6-434% -3½ -105BetMGM | |||||||
 Northwestern 5-540% -3½ -110BetMGM | |||||||
 #3Texas A&M 10-0- -54½ -110Bet365 | |||||||
 #4Georgia 9-163% -43½ -112Caesars | |||||||
 Georgia Southern 5-556% +11 -115SugarHouse | |||||||
 James Madison 9-149% -13½ -120FanDuel | |||||||
 Arizona 7-331% -6½ -114Caesars | |||||||
 Toledo 6-469% -27½ -110Bet365 | |||||||
 Wyoming 4-626% -6½ -112Caesars | |||||||
 Kennesaw State 7-321% -6½ -105FanDuel | |||||||
 Auburn 4-6- -27½ -110Bet365 | |||||||
 #10Alabama 8-2- -50½ -107Caesars | |||||||
 Appalachian State 4-673% +5½ -115Caesars | |||||||
 Florida Atlantic 4-684% +7½ -120FanDuel | |||||||
 UTEP 2-824% -3 -113Caesars | |||||||
 Middle Tennessee 1-950% -6½ -113BetRivers | |||||||
 Louisiana Tech 5-524% +1½ -115FanDuel | |||||||
 UAB 3-773% +21½ -109Caesars | |||||||
 North Carolina 4-671% +7 -115BetMGM | |||||||
 #17Texas 7-313% -8 -115BetRivers | |||||||
 #7Oregon 9-160% -10 -110Bet365 | |||||||
 Iowa 6-459% -16½ -110Bet365 | |||||||
 UTSA 5-567% +2½ -108Caesars | |||||||
 #14Vanderbilt 8-217% -8 -115SugarHouse | |||||||
 South Alabama 3-757% +1½ -115BetMGM | |||||||
 Florida International 5-560% -1 -115Bet365 | |||||||
 #9Notre Dame 8-272% -35 -110Bet365 | |||||||
 Temple 5-584% +9½ -105FanDuel | |||||||
 UCF 4-623% -13 -110Bet365 | |||||||
 Maryland 4-672% +14 -107Caesars | |||||||
 #23Houston 8-228% -1 -113BetRivers | |||||||
 #12Utah 8-269% -15½ -125BetMGM | |||||||
 Troy 6-423% -9½ -118FanDuel | |||||||
 South Carolina 3-759% -23½ -122FanDuel | |||||||
 Clemson 5-5- -41½ -110Caesars | |||||||
 Texas State 4-629% -19½ -110Bet365 | |||||||
 #16Georgia Tech 9-117% -2½ -110Bet365 | |||||||
 Penn State 4-634% -7½ -113BetRivers | |||||||
 Boise State 6-40% -16½ -110Bet365 | |||||||
 Air Force 3-789% +4 -120SugarHouse | |||||||
 Florida 3-788% +4½ -112BetRivers | |||||||
 Stanford 3-781% +3½ -113Caesars | |||||||
 Wisconsin 3-757% +8½ -110BetMGM | |||||||
 Rice 5-588% +18½ -115FanDuel | |||||||
 LSU 6-48% -21½ -110Bet365 | |||||||
 Cincinnati 7-338% +3 -113Caesars | |||||||
 Colorado 3-785% +7½ -115Bet365 | |||||||
 UCLA 3-787% +10½ -110Bet365 | |||||||
 San Diego State 8-211% -11½ -114FanDuel | |||||||
 Fresno State 7-317% -2½ -115Bet365 | |||||||
 Ohio 7-442 -33½ -115BetRivers | |||||||
 Bowling Green 3-816 -2½ -110Bet365 | |||||||
 Northern Illinois 3-819 +7½ -122FanDuel | |||||||
 Buffalo 5-620 +2½ -107Caesars | |||||||
 Kent State 4-716 +8½ -115FanDuel | |||||||
 Arkansas State 5-630 -2½ -110Bet365 | |||||||
 North Carolina State 6-521 +7 -118SugarHouse | |||||||
 UNLV 9-238 -2 -121SugarHouse |
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